X0708 D LIVE 0001626199 ALPINE IMMUNE SCIENCES, INC. 188 EAST BLAINE ST., SUITE 200 SEATTLE WA WASHINGTON 98102 206-788-4545 DELAWARE Nivalis Therapeutics, Inc. N30 Pharmaceuticals, Inc. Corporation true James Paul Rickey 188 EAST BLAINE ST., SUITE 200 SEATTLE WA WASHINGTON 98102 Executive Officer Senior Vice President and Chief Financial Officer Mitchell Gold 188 EAST BLAINE ST., SUITE 200 Seattle WA WASHINGTON 98102 Executive Officer Director Executive Chairman and Chief Executive Officer Stanford Peng 188 EAST BLAINE ST., SUITE 200 SEATTLE WA WASHINGTON 98102 Executive Officer President and Head of Research and Development Robert Conway 188 EAST BLAINE ST., SUITE 200 SEATTLE WA WASHINGTON 98102 Director Christopher Peetz 188 EAST BLAINE ST., SUITE 200 SEATTLE WA WASHINGTON 98102 Director Paul Sekhri 188 EAST BLAINE ST., SUITE 200 Seattle WA WASHINGTON 98102 Director Peter Thompson 188 EAST BLAINE ST., SUITE 200 SEATTLE WA WASHINGTON 98102 Director James Topper 188 EAST BLAINE ST., SUITE 200 SEATTLE WA WASHINGTON 98102 Director Jay Venkatesan 188 EAST BLAINE ST., SUITE 200 SEATTLE WA WASHINGTON 98102 Director Cui Xiangmin 188 EAST BLAINE ST., SUITE 200 SEATTLE WA WASHINGTON 98102 Director Biotechnology Decline to Disclose 06b false 2020-07-28 false true true true false 0 Cowen and Company 7616 None None 599 Lexington Avenue, 20th Floor New York NY NEW YORK 10022 CA CALIFORNIA IL ILLINOIS MA MASSACHUSETTS NY NEW YORK PA PENNSYLVANIA TX TEXAS true Oppenheimer & Co. Inc. 249 None None 85 Broad Street 22nd, 24th Floor New York NY NEW YORK 10004 CA CALIFORNIA IL ILLINOIS MA MASSACHUSETTS NY NEW YORK PA PENNSYLVANIA TX TEXAS true 82666486 60000013 22666473 5,930,320 units were sold at a price per unit of $10.1175. Each unit consisted of a share of common stock, or a prefunded warrant to purchase one share, and a warrant to purchase 0.3 shares of common stock at exercise price per share of $12.74. false 25 3340002 0 0 false ALPINE IMMUNE SCIENCES, INC. /s/James Paul Rickey James Paul Rickey Senior VP and CFO 2020-08-07