<SEC-DOCUMENT>0000899243-19-001663-index.html : 20190122
<SEC-HEADER>0000899243-19-001663.hdr.sgml : 20190122
<ACCEPTANCE-DATETIME>20190122204629
ACCESSION NUMBER:		0000899243-19-001663
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20190118
FILED AS OF DATE:		20190122
DATE AS OF CHANGE:		20190122

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Alpine ImmunoSciences, L.P.
		CENTRAL INDEX KEY:			0001628571
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37449
		FILM NUMBER:		19536404

	BUSINESS ADDRESS:	
		STREET 1:		600 STEWART STREET
		STREET 2:		SUITE 1503
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98101
		BUSINESS PHONE:		206-441-5064

	MAIL ADDRESS:	
		STREET 1:		600 STEWART STREET
		STREET 2:		SUITE 1503
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98101

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Alpine Bioventures, GP, LLC
		CENTRAL INDEX KEY:			0001712676
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37449
		FILM NUMBER:		19536405

	BUSINESS ADDRESS:	
		STREET 1:		600 STEWART STREET
		STREET 2:		SUITE 1503
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98101
		BUSINESS PHONE:		206-441-5064

	MAIL ADDRESS:	
		STREET 1:		600 STEWART STREET
		STREET 2:		SUITE 1503
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98101

	FORMER NAME:	
		FORMER CONFORMED NAME:	Alpine Bioventures GP, LLC
		DATE OF NAME CHANGE:	20170724

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ALPINE IMMUNE SCIENCES, INC.
		CENTRAL INDEX KEY:			0001626199
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				208969493
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		201 ELLIOTT AVE. WEST, SUITE 230
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98119
		BUSINESS PHONE:		206-788-4545

	MAIL ADDRESS:	
		STREET 1:		201 ELLIOTT AVE. WEST, SUITE 230
		CITY:			SEATTLE
		STATE:			WA
		ZIP:			98119

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Nivalis Therapeutics, Inc.
		DATE OF NAME CHANGE:	20150211

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	N30 Pharmaceuticals, Inc.
		DATE OF NAME CHANGE:	20141121
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>doc4.xml
<DESCRIPTION>FORM 4 SUBMISSION
<TEXT>
Document 1 - file: doc4.html

Document 1 - RAW XML: doc4.xml

</DOCUMENT>
</SEC-DOCUMENT>