X0306 4 2020-04-28 0 0001583107 Theravance Biopharma, Inc. TBPH 0001625377 O'Connor Donal C/O THERAVANCE BIOPHARMA US, INC 901 GATEWAY BLVD SOUTH SAN FRANCISCO CA 94080 1 0 0 0 Ordinary Shares 2020-04-28 4 A 0 6635 0 A 34206 D Share Option (Right to Buy) 30.14 2020-04-28 4 A 0 6000 0 A 2030-04-27 Ordinary Shares 6000 6000 D This option may be exercised and shall be vested as to 1/12th of the shares subject to this option when optionee completes each continuous month of service following the grant date and any then remaining unvested shares shall vest on the date of the next annual meeting of the Company's shareholders provided the optionee remains in continuous service on such date. Brett A. Grimaud, Attorney-in-Fact 2020-04-30