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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2021
Income Taxes [Abstract]  
Income (Loss) Before Income Taxes Year Ended December 31, 2021 2020 2019Domestic $ (63,660) $ (49,851) $ (46,971)Foreign — — — $ (63,660) $ (49,851) $ (46,971)
Components of Income Tax Expense (Benefit) December 31, 2021 2020 2019Current Federal $ — $ — $ —State 3 3 3Foreign — — —Total current 3 3 3 Deferred Federal — — —State — — —Foreign — — —Total deferred — — — Total provision for income taxes $ 3 $ 3 $ 3
Reconcilement Of Tax Rates Year Ended December 31, 2021 2020 2019Federal tax at statutory rate 21.0% 21.0% 21.0%State tax (benefit) at statutory rate 8.4 8.4 (5.0) Research and development credits 1.9 2.1 2.0 Change in valuation allowance (26.8) (43.3) (18.0) Deferred adjustment — 8.5 — Change in tax rate — 4.2 — Uncertain Tax Position (2.3) — — Other (2.2) (0.8) — Provision for income taxes —% —% —%
Components Of Deferred Tax Assets December 31, 2021 2020Deferred tax assets Accruals $ 1,034 $ 894Net operating loss carryforwards 49,246 36,531Tax credit carryforwards 6,611 5,431Stock-based compensation 12,188 9,391Lease liability under ASC 842 3,182 3,339Gross deferred tax assets 72,261 55,586Valuation allowance (69,006) (51,973)Total deferred tax assets 3,255 3,613 Deferred tax liabilities Intangibles (365) (486)ROU asset under ASC 842 (2,862) (3,096)Fixed assets (28) (31)Total deferred tax liabilities (3,255) (3,613) Net deferred tax assets/(liabilities) $ — $ —
Reconciliation Of Unrecognized Tax Benefit Accounts December 31, 2021 2020 2019Unrecognized tax benefits at beginning of year $ 2,491 $ 1,470 $ 877Increases related to current year tax positions 2,649 1,021 593Unrecognized tax benefits at end of year $ 5,140 $ 2,491 $ 1,470