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Condensed Consolidated Statements Of Cash Flows - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2020
Mar. 31, 2019
Cash flows from operating activities:    
Net loss $ (11,872) $ (10,078)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 104 162
Amortization of intangible assets 166 167
Stock-based compensation 2,626 2,361
Net premium amortization and discount on available-for-sale securities (4) (96)
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets 460 229
Right-of-use assets 71  
Other long-term assets (68) (107)
Accounts payable (749) (72)
Accrued expenses (425) 98
Lease liabilities 69  
Other current and non-current liabilities   6
Net cash used in operating activities (9,622) (7,330)
Cash flows from investing activities:    
Purchases of property and equipment (171) (45)
Purchases of investments (3,006) (44,186)
Maturities of investments 13,500 8,500
Net cash provided by (used) in investing activities 10,323 (35,731)
Cash flows from financing activities:    
Proceeds from issuance of common stock under employee stock purchase plan 255 272
Proceeds from exercises of stock options 9 222
Net cash provided by financing activities 264 494
Net increase (decrease) in cash 965 (42,567)
Cash and cash equivalents at beginning of period 6,899 51,103
Cash and cash equivalents at end of period 7,864 8,536
Supplemental disclosure of noncash investing and financing activities:    
Change in unrealized gains on available-for-sale securities $ 13 $ 3