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Note 4 - Balance Sheet Components (Tables)
6 Months Ended
Jun. 30, 2025
Notes Tables  
Property, Plant and Equipment [Table Text Block]
  

June 30,

  

December 31,

 
  

2025

  

2024

 

Leasehold improvements

 $2,519  $2,519 

Laboratory equipment

  1,482   1,342 

Furniture, fixtures and equipment

  966   966 

Software

  283   272 

Construction in progress

  50   29 

Total property and equipment

  5,300   5,128 

Less: Accumulated depreciation and amortization

  (4,191)  (3,968)

Total property and equipment, net

 $1,109  $1,160 
Schedule of Finite-Lived Intangible Assets [Table Text Block]
  

June 30,

  

December 31,

 
  

2025

  

2024

 

Acquired patents and licenses

 $8,005  $7,985 

Less: Accumulated amortization

  (7,098)  (6,765)

Total intangible assets, net

 $907  $1,220 
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]

Years ending December 31:

    

2025 (remaining 6 months)

 $332 

2026

  575 

Total

 $907 
Schedule of Accrued Liabilities [Table Text Block]
  

June 30,

  

December 31,

 
  

2025

  

2024

 

Compensation expense

 $3,473  $4,097 

Professional fees

  659   564 

Clinical trial fees and costs

  433   284 

Other

  212   188 

Legal settlement

     1,196 

Severance

     698 

Total accrued expenses

 $4,777  $7,027