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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Cash flows from operating activities:      
Net loss $ (58,505) $ (63,660) $ (49,851)
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation 690 480 430
Amortization of intangible assets 665 666 665
Stock-based compensation 5,191 14,601 10,075
Write-off of excessive and obsolete inventory 8,477 0 0
Net premium amortization and discount on available-for-sale securities 0 13 5
Loss on disposal of fixed assets 185 0 119
Gain on U.S. Treasury securities 0 0 (8)
Changes in operating assets and liabilities:      
Accounts receivable 61 (61) 0
Inventory (2,653) (5,824) 0
Prepaid expenses and other current assets 1,164 (1,374) 194
Other receivables (41) 54 0
Right-of-use assets 723 653 509
Other long-term assets 0 0 129
Accounts payable (1,304) 1,160 (266)
Accrued expenses (1,794) (937) 2,830
Deferred revenue (16) 16 0
Lease liabilities (774) (542) (196)
Accrued interest on related party note payable 917 0 0
Accrued interest on note payable 1 658 0
Net cash used in operating activities (47,013) (54,097) (35,365)
Cash flows from investing activities:      
Purchases of property and equipment (401) (437) (441)
Purchases of investments 0 0 (29,025)
Maturities of investments 0 8,000 35,000
Sales of investments 0 0 4,510
Net cash provided by (used in) investing activities (401) 7,563 10,044
Cash flows from financing activities:      
Proceeds from issuance of common stock under employee stock purchase plan 486 810 490
Proceeds from exercises of warrants 26 4,217 244
Proceeds from exercises of stock options 0 786 717
Proceeds from issuance of common stock 14,864 56,697 29,434
Proceeds from issuance of related party note 65,000 0 0
Proceeds from insurance loan agreement 0 1,939 0
Payments made on insurance loan agreement (437) (1,532) 0
Tax payments related to shares withheld for vested restricted stock units 0 (232) 0
Net cash provided by financing activities 79,939 62,685 30,885
Net increase in cash and cash equivalents 32,525 16,151 5,564
Cash and cash equivalents at beginning of period 28,614 12,463 6,899
Cash and cash equivalents at end of period 61,139 28,614 12,463
Supplemental disclosure of noncash investing and financing activities:      
Other receivable from exercise of warrants and stock options 0 0 1,053
Change in unrealized gains on available-for-sale securities 0 1 (5)
Equipment purchases included in accounts payable and accrued expenses (27) (27) (20)
Equipment purchases included in accounts payable and accrued expenses 27 27 20
Accrued interest settled via issuance of common stock from private placement equity offering $ 0 $ 629 $ 0