X0306 4 2018-04-02 0 0001624899 STERIS plc STE 0001697095 Burton Karen L C/O RUTHERFORD HOUSE, STEPHENSONS WAY CHADDESDEN DERBY X0 DE21 6LY UNITED KINGDOM 0 1 0 0 VP, Controller & CAO Ordinary Shares, 10 pence par value 2018-04-02 4 F 0 293 91.02 D 8244 D Ordinary Shares, 10 pence par value 324 I By 401(k) 293 shares were withheld from the 1,000 restricted shares that vested on April 2, 2018. These 293 ordinary shares represent the value of the taxes required to be withheld pursuant to applicable employment or tax laws, as determined by the Issuer. These 1,000 ordinary shares were awarded to Ms. Burton on March 31, 2014. These vested shares were valued at the NYSE closing market price on April 2, 2018. 6,656 of these shares are restricted and vest as follows: 972 on May 30, 2018; 764 on May 28, 2019; 700 on October 1, 2019; 1,220 on June 1, 2020 and 3,000 on June 1, 2021. Based on closing price of $91.02 per share on April 2, 2018. /s/ Ronald E. Snyder, Authorized Representative under Power of Attorney 2018-04-04