Commitments and Contingencies - Additional Information (Details)	12 Months Ended
	Dec. 31, 2021 USD ($) ft² shares	Dec. 31, 2020 USD ($)
Operating Leased Assets [Line Items]
Lease costs	$ 400,000	$ 500,000
Operating lease, weighted average remaining lease term	1 year 3 months 18 days	2 years 3 months 18 days
Operating lease, weighted average discount rate	5.50%	5.50%
Althea Technologies, Inc
Operating Leased Assets [Line Items]
Contract termination period	60 days
Althea Technologies, Inc | License Agreement | Maximum
Operating Leased Assets [Line Items]
Potential milestone payable	$ 56,000,000.0
Patents | Althea Technologies, Inc | License Agreement
Operating Leased Assets [Line Items]
Fees and costs incurred	$ 100,000
Type of Cost, Good or Service [Extensible List]	us-gaap:LicenseMember
Common stock, shares issued | shares	88,186
Newton, MA
Operating Leased Assets [Line Items]
Rentable office space under operating lease | ft²	6,055
Base rent for office space	$ 300,000
Right to terminate description	The Newton Lease terminates on the last day of the month following the month either party notifies the other that the term of the lease shall end.
Sudbury, MA
Operating Leased Assets [Line Items]
Rentable office space under operating lease | ft²	11,691
Base rent for office space	$ 300,000
Operating lease expiration date	Feb. 28, 2026
Right to terminate description	The Company has a one-time option to cancel the lease effective February 28, 2023 for any reason or no reason at all.