Exhibit 15.1

KPMG Audit 51 rue de Saint-Cyr
CS 60409
69338 Lyon Cedex 9
France   Téléphone : Téléphone : Site internet : +33 (0)4 37 64 76 00 +33 (0)4 37 64 76 09 www.kpmg.fr

Consent of Independent Registered Public Accounting Firm

The Board of Directors,

Erytech Pharma S.A.

We consent to the incorporation by reference in the registration statement (no. 333-222673) on Form S-8 of Erytech Pharma S.A. of our report dated March 28, 2019, with respect to the consolidated statements of financial position of Erytech Pharma S.A. and its subsidiary as of December 31, 2018, 2017 and 2016, and the related consolidated statements of income (loss), comprehensive income (loss), changes in shareholders’ equity  and cash flows for each of the years in the three-year period ended December 31, 2018, and the related notes (collectively, the “consolidated financial statements”), which report appears in the Annual Report on Form 20-F of Erytech Pharma S.A. for the year ended December 31, 2018.

Lyon, March 29, 2019

KPMG Audit

A division of KPMG S.A.

/s/ Sara Righenzi de Villers

Partner

KPMG S.A.,
société française membre du réseau KPMG
constitué de cabinets indépendants adhérents de
KPMG International Cooperative, une entité de droit suisse. Société anonyme d’expertise
comptable et de commissariat
aux comptes à directoire et
conseil de surveillance.
Inscrite au Tableau de l’Ordre
à Paris sous le n° 14-30080101
et à la Compagnie Régionale
des Commissaires aux Comptes
de Versailles. Siège social :
KPMG S.A.
Tour Eqho
2 avenue Gambetta
92066 Paris la Défense Cedex
Capital : 5 497 100 €.
Code APE 6920Z
775 726 417 R.C.S. Nanterre
TVA Union Européenne
FR 77 775 726 417