X0306 4 2022-06-01 0 0001623715 Imago BioSciences, Inc. IMGO 0001249153 HENNER DENNIS C/O IMAGO BIOSCIENCES, INC. 329 OYSTER POINT BLVD, 3RD FLOOR SOUTH SAN FRANCISCO CA 94080 1 0 0 0 Common Stock 26095 D Stock Option (Right to Buy) 15.65 2022-06-01 4 A 0 11904 0 A 2032-05-31 Common Stock 11904 0 D Includes 26,095 shares of Common Stock received from Clarus Ventures III GP, L.P. in a pro rata distribution in-kind. The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or the day prior to the annual meeting in 2023 of the Issuer's stockholders, assuming continuous service as a director until such vesting date. The Reporting Person disclaims beneficial ownership of these securities and the inclusion of the securities in this report shall not be deemed an admission of beneficial ownership for purposes of Section 16 or any other purpose. The Reporting Person is an employee of Blackstone Inc. or one of its Affiliates ("Blackstone"). Pursuant to arrangements between the Reporting Person and Blackstone, the Reporting Person is required to transfer to Blackstone any and all compensation received in connection with his directorship for any company Blackstone invests in or advises. Mr. Henner, an Executive Advisor to Blackstone or one of its affiliates, is a member of the board of directors of the Issuer. Mr. Henner disclaims beneficial ownership of any securities of the Issuer that may be deemed to be beneficially owned by affiliates of Blackstone. /s/ Hugh Rienhoff, Jr., as Attorney-in-fact for Dennis Henner 2022-06-03