X0306 4 2022-02-11 0 0001623715 Imago BioSciences, Inc. IMGO 0001861067 Eichorn Laura G. C/O IMAGO BIOSCIENCES, INC. 329 OYSTER POINT BLVD, 3RD FLOOR SOUTH SAN FRANCISCO CA 94080 0 1 0 0 See Remarks Common Stock 2022-02-11 4 M 0 4000 1.52 A 211737 D Common Stock 2022-02-11 4 S 0 4000 23.6137 D 207737 D Stock Option (Right to Buy) 1.52 2022-02-11 4 M 0 4000 0.00 D 2029-04-09 Common Stock 4000 34595 D Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person. The transaction was executed in multiple trades in prices ranging from $23.50 to $23.74, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. One forty-eighth (1/48th) of the shares initially subject to the option will vest on each monthly anniversary measured from April 10, 2019 (the "Vesting Commencement Date"), so that 100% of the shares subject to the option will be fully vested and exercisable as of the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date. Chief Operating Officer/Interim CFO /s/ Hugh Rienhoff, as Attorney-in-fact for Laura Eichorn 2022-02-15