X0306 4 2021-06-28 1 0001623526 Stoke Therapeutics, Inc. STOK 0001593440 ATP Life Science Ventures, L.P. C/O APPLE TREE PARTNERS 230 PARK AVENUE, 28TH FLOOR NEW YORK NY 10169 0 0 1 0 0001593453 ATP III GP, Ltd. C/O APPLE TREE PARTNERS 230 PARK AVENUE, 28TH FLOOR NEW YORK NY 10169 0 0 1 0 Common Stock 2021-06-28 4 J 0 17161713 D 0 D The shares were distributed in a pro rata distribution to the limited partners of ATP Life Science Ventures, L.P. ("ATP," and formerly known as Apple Tree Partners IV, L.P.). The shares were directly held by ATP. ATP III GP, Ltd. ("ATP GP") is the sole general partner of ATP. Seth L. Harrison is a director on the Issuer's board of directors and is the sole director of ATP GP. ATP GP and Dr. Harrison disclaim beneficial ownership of the reported shares, except to the extent of any pecuniary interest therein. /s/ Seth L. Harrison, for ATP Life Science Ventures, L.P., By: Seth L. Harrison, as director of ATP III GP, Ltd., its general partner 2021-06-30 /s/ Seth L. Harrison, for ATP III GP, Ltd., By: Seth L. Harrison, director 2021-06-30