<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:ns1="http://www.sec.gov/edgar/common">
  <schemaVersion>X0202</schemaVersion>
<headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <previousAccessionNumber>0000947263-25-000009</previousAccessionNumber>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0000947263</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>1</amendmentNo>
      <securitiesClassTitle>Common Stock, $0.0001 par value per share</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>03/31/2026</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001623526</issuerCik>
        <issuerName>Stoke Therapeutics, Inc.</issuerName>
        <issuerCusips>
          <issuerCusipNumber>86150R107</issuerCusipNumber>
        </issuerCusips>
        <issuerPrincipalExecutiveOfficeAddress>
          <ns1:street1>45 WIGGINS AVENUE</ns1:street1>
          <ns1:city>BEDFORD</ns1:city>
          <ns1:stateOrCountry>MA</ns1:stateOrCountry>
          <ns1:zipCode>01730</ns1:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(b)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>The Toronto-Dominion Bank</reportingPersonName>
      <citizenshipOrOrganization>Z4</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>3173258</soleVotingPower>
        <sharedVotingPower>0</sharedVotingPower>
        <soleDispositivePower>3173258</soleDispositivePower>
        <sharedDispositivePower>0</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>3173258</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>5.4</classPercent>
      <typeOfReportingPerson>FI</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>TD Securities Inc.</reportingPersonName>
      <citizenshipOrOrganization>A6</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>2300</soleVotingPower>
        <sharedVotingPower>0</sharedVotingPower>
        <soleDispositivePower>2300</soleDispositivePower>
        <sharedDispositivePower>0</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>2300</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>0</classPercent>
      <typeOfReportingPerson>FI</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>Stoke Therapeutics, Inc.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>45 WIGGINS AVENUE, BEDFORD, MASSACHUSETTS
01730</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>The Toronto-Dominion Bank

TD Securities Inc.</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>The principal office address of The Toronto-Dominion Bank ("TD Bank"):

66 Wellington Street West
12th Floor TD Tower
Toronto, Ontario, Canada
M5K 1A2

The principal office address of TD Securities Inc. ("TDSI"):

55 King Street West
TD Tower 12th Floor
Toronto, Ontario, Canada
M5K 1A2
</principalBusinessOfficeOrResidenceAddress>
        <citizenship>The Toronto-Dominion Bank - CANADA (FEDERAL LEVEL)

TD Securities Inc. - ONTARIO, CANADA</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>N</notApplicableFlag>
        <typeOfPersonFiling>FI</typeOfPersonFiling>
        <otherTypeOfPersonFiling>TD Bank - Bank
TDSI - Broker Dealer
</otherTypeOfPersonFiling>
      </item3>
      <item4>
        <amountBeneficiallyOwned>3,175,558

TD Bank has the sole power to vote or direct the vote and the sole power to dispose or direct the disposition of 3,173,258 of these shares and
TDSI has the sole power to vote or direct the vote and the sole power to dispose or direct the disposition of 2,300 of these shares.

This schedule is jointly filed by TD Bank and TDSI. TD Bank is the sole owner of TDSI. TD Bank may be deemed to hold an indirect interest in the shares reported herein by TDSI by virtue of its ownership of TDSI. TD Bank disclaims ownership of the shares reported herein by TDSI except to the extent of its pecuniary interest therein.

Each reporting person declares that neither the filing of this statement nor anything herein shall be construed as an admission that such person is, for the purposes of Section 13(d) of the US Securities Exchange Act of 1934 or any other purpose, (i) acting (or has agreed or is agreeing to act together with any other person) as a partnership, limited partnership, syndicate or other group for the purpose of acquiring, holding or disposing of securities of the Issuer or otherwise with respect to the Issuer or any securities of the Issuer or (ii) a member of any group with respect to the Issuer or any securities of the Issuer.
</amountBeneficiallyOwned>
        <classPercent>5.4</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>The Toronto-Dominion Bank - 3,173,258

TD Securities Inc. - 2,300</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>The Toronto-Dominion Bank - 0

TD Securities Inc. - 0</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>The Toronto-Dominion Bank - 3,173,258

TD Securities Inc. - 2,300</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>The Toronto-Dominion Bank - 0

TD Securities Inc. - 0</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>Y</notApplicableFlag>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
      </item10>
    </items>
    <exhibitInfo>Exhibit I

JOINT FILING AGREEMENT

This will confirm the agreement by and among the undersigned that the Schedule 13G filed with the Securities and Exchange Commission on or about the date hereof with respect to the beneficial ownership by the undersigned of the common stock of Stoke Therapeutics Inc. will be filed on behalf of each of the persons and entities named below in accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument.

Dated: May 15, 2026


THE TORONTO-DOMINION BANK

By: /s/ Christina Petrou
Title: Executive Vice President &amp; Chief Operating Officer


TD SECURITIES INC.

By: /s/ Greg Nowakowski
Title:  Chief Compliance Officer</exhibitInfo>
    <signatureInformation>
      <reportingPersonName>The Toronto-Dominion Bank</reportingPersonName>
      <signatureDetails>
        <signature>Christina Petrou</signature>
        <title>Christina Petrou / Executive Vice President &amp; Chief Operating Officer</title>
        <date>05/15/2026</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>TD Securities Inc.</reportingPersonName>
      <signatureDetails>
        <signature>Greg Nowakowski</signature>
        <title>Greg Nowakowski / Chief Compliance Officer</title>
        <date>05/15/2026</date>
      </signatureDetails>
    </signatureInformation>
  </formData>
</edgarSubmission>
