ACORDA THERAPEUTICS INC COM 00484M106 404 25957 SH DFND 1, 2, 3, 4 25957 0 0 ALARM COM HLDGS INC COM 011642105 6224 120000 SH DFND 1, 2, 3, 4 120000 0 0 AMAZON COM INC COM 023135106 9012 6000 SH DFND 1, 2, 3, 4 6000 0 0 ARES CAP CORP COM 04010L103 1605 103030 SH DFND 1, 2, 3, 4 103030 0 0 AXSOME THERAPEUTICS INC COM 05464T104 56 19958 SH DFND 1, 2, 3, 4 19958 0 0 ALPHABET INC CAP STK CL A 02079K305 28214 27000 SH DFND 1, 2, 3, 4 27000 0 0 AVIS BUDGET GROUP COM 053774105 11913 529957 SH DFND 1, 2, 3, 4 529957 0 0 BEACON ROOFING SUPPLY INC COM 073685109 2069 65240 SH DFND 1, 2, 3, 4 65240 0 0 BLACKROCK INC COM 09247X101 8727 22216 SH DFND 1, 2, 3, 4 22216 0 0 BLACKSTONE GROUP L P COM UNIT LTD 09253U108 6893 231240 SH DFND 1, 2, 3, 4 231240 0 0 CARA THERAPEUTICS INC COM 140755109 715 54984 SH DFND 1, 2, 3, 4 54984 0 0 CARTERS INC COM 146229109 4360 53414 SH DFND 1, 2, 3, 4 53414 0 0 CHARLES RIV LABS INTL INC COM 159864107 250 2207 SH DFND 1, 2, 3, 4 2207 0 0 CLOUDERA INC COM 18914U100 13588 1228553 SH DFND 1, 2, 3, 4 1228553 0 0 COMMUNITY HEALTH SYS INC NEW COM 203668108 77506 27484473 SH DFND 1, 2, 3, 4 27484473 0 0 CRISPR THERAPEUTICS AG NAMEN AKT H17182108 1662 58158 SH DFND 1, 2, 3, 4 58158 0 0 DOLLAR GEN CORP NEW COM 256677105 3242 30000 SH DFND 1, 2, 3, 4 30000 0 0 DROPBOX INC CL A 26210C104 2043 100000 SH DFND 1, 2, 3, 4 100000 0 0 EDITAS MEDICINE INC COM 28106W103 1219 53579 SH DFND 1, 2, 3, 4 53579 0 0 ELLIE MAE INC COM 28849P100 1257 20000 SH DFND 1, 2, 3, 4 20000 0 0 ENBRIDGE INC COM 29250N105 2228 71700 SH DFND 1, 2, 3, 4 71700 0 0 GREENSKY INC CL A 39572G100 1516 158427 SH DFND 1, 2, 3, 4 158427 0 0 HORTONWORKS INC COM 440894103 4478 310558 SH DFND 1, 2, 3, 4 310558 0 0 HERCULES CAPITAL INC COM 427096508 23231 2102327 SH DFND 1, 2, 3, 4 2102327 0 0 ICON PLC SHS G4705A100 323 2499 SH DFND 1, 2, 3, 4 2499 0 0 INSTRUCTURE INC COM 45781U103 1125 30000 SH DFND 1, 2, 3, 4 30000 0 0 INTELLIA THERAPEUTICS INC COM 45826J105 664 48657 SH DFND 1, 2, 3, 4 48657 0 0 INTRA CELLULAR THERAPIES INC COM 46116X101 402 35278 SH DFND 1, 2, 3, 4 35278 0 0 IQVIA HLDGS INC COM 46266C105 1072 9224 SH DFND 1, 2, 3, 4 9224 0 0 KINDER MORGAN INC DEL COM 49456B101 3991 259500 SH DFND 1, 2, 3, 4 259500 0 0 KKR & CO INC CL A 48251W104 30389 1548100 SH DFND 1, 2, 3, 4 1548100 0 0 LABORATORY CORP AMER HLDGS COM NEW 50540R409 586 4636 SH DFND 1, 2, 3, 4 4636 0 0 LEGG MASON INC COM 524901105 5153 202000 SH DFND 1, 2, 3, 4 202000 0 0 LENDINGCLUB CORP COM 52603A109 257252 97814405 SH DFND 1, 2, 3, 4 97814405 0 0 MARINUS PHARMACEUTICALS INC COM 56854Q101 29 10000 SH DFND 1, 2, 3, 4 10000 0 0 MEDPACE HLDGS INC COM 58506Q109 87 1638 SH DFND 1, 2, 3, 4 1638 0 0 NEUROCRINE BIOSCIENCES INC COM 64125C109 714 10000 SH DFND 1, 2, 3, 4 10000 0 0 PRA HEALTH SCIENCES INC COM 69354M108 274 2980 SH DFND 1, 2, 3, 4 2980 0 0 PTC THERAPEUTICS INC COM 69366J200 1041 30332 SH DFND 1, 2, 3, 4 30332 0 0 SANGAMO THERAPEUTICS INC COM 800677106 1313 114410 SH DFND 1, 2, 3, 4 114410 0 0 SYNEOS HEALTH INC CL A 87166B102 186 4735 SH DFND 1, 2, 3, 4 4735 0 0 SUPERNUS PHARMACEUTICALS INC COM 868459108 332 10000 SH DFND 1, 2, 3, 4 10000 0 0 SELECT SECTOR SPDR TR SBI HEALTHCARE 81369Y209 1944 22471 SH DFND 1, 2, 3, 4 22471 0 0 TARGA RES CORP COM 87612G101 2626 72900 SH DFND 1, 2, 3, 4 72900 0 0 TELADOC HEALTH INC COM 87918A105 1775 35800 SH DFND 1, 2, 3, 4 35800 0 0 TAPESTRY INC COM 876030107 2419 71666 SH DFND 1, 2, 3, 4 71666 0 0 UNITED RENTALS INC COM 911363109 5473 53376 SH DFND 1, 2, 3, 4 53376 0 0 VANDA PHARMACEUTICALS INC COM 921659108 1170 44787 SH DFND 1, 2, 3, 4 44787 0 0 WESTERN DIGITAL CORP COM 958102105 1479 40000 SH DFND 1, 2, 3, 4 40000 0 0 ZOGENIX INC COM NEW 98978L204 365 10000 SH DFND 1, 2, 3, 4 10000 0 0