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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Cash flows from operating activities:    
Net loss $ (72,273) $ (74,808)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization expense 147 720
Stock-based compensation expense 11,686 6,017
Noncash consideration received from a customer   (808)
Noncash portion of acquired in-process research and development   44,813
Gain on disposal of long-lived assets   (7,493)
Change in fair value of CVR liability (343) 1,025
Changes in operating assets and liabilities:    
Accounts receivable   2,000
Prepaid expenses and other current assets (227) (1,470)
Operating lease, right-of-use asset 1,844 670
Other assets (3,727) 427
Accounts payable 2,751 (2,451)
Accrued expenses and other current liabilities 3,431 (2,352)
Operating lease liability (2,052) (825)
Deferred revenue   (1,315)
Net cash used in operating activities (58,763) (35,850)
Cash flows from investing activities:    
Purchases of property and equipment (1,719)  
Proceeds from sale of property and equipment   320
Proceeds from sale of BOXR Platform assets   8,100
Net cash (used in) provided by investing activities (1,719) 8,420
Cash flows from financing activities:    
Proceeds from the issuance of Series A non-voting convertible preferred stock, net of issuance costs of $5,493   98,907
Proceeds from issuance of common stock to LPC   25,000
Proceeds from issuance of common stock under ATM, net of issuance costs of $1,229 38,006  
Proceeds from issuance of common stock in underwritten public offering, net of offering costs of $7,271   107,729
Proceeds from issuance of common stock upon stock option exercises 24 512
Proceeds from issuance of stock from employee stock purchase plan 31 48
Payments to CVR Holders (85)  
Net cash provided by financing activities 37,976 232,196
Net (decrease) increase in cash, cash equivalents and restricted cash (22,506) 204,766
Cash, cash equivalents and restricted cash at beginning of period 243,445 38,679
Cash, cash equivalents and restricted cash at end of period 220,939 243,445
Supplemental disclosure of noncash investing and financing information:    
Conversion of Series A non-voting convertible preferred stock into common stock 25,481 27,351
Issuance of common shares in partial settlement of CVR liability $ 2,043 $ 6,944