Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2025	Jun. 30, 2024
Cash flows from operating activities:
Net loss	$ (145,515)	$ (117,298)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization expense	1,295	1,205
Stock-based compensation expense	19,724	19,405
Amortization of operating leases, right-of-use assets	1,000	941
Net amortization (accretion) of premiums (discounts) on marketable securities	(739)	1,185
Amortization of long-term debt discount and issuance costs	63
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	2,235	(1,694)
Other assets	0	(2)
Accounts payable	4,612	(1,680)
Accrued expenses and other current liabilities	(2,979)	3,377
Operating lease liability	(758)	(669)
Other liabilities	9
Net cash used in operating activities	(121,053)	(95,230)
Cash flows from investing activities:
Purchases of property and equipment	(678)	(218)
Purchases of marketable securities	(67,883)	(223,411)
Maturities and sales of marketable securities	146,850	140,048
Net cash provided by (used in) investing activities	78,289	(83,581)
Cash flows from financing activities:
Proceeds from long-term debt	49,291
Payment of debt issuance costs	(2,069)
Proceeds from issuance of common stock under ATM, net of issuance costs of $0.7 million	24,250
Proceeds from issuance of common stock and Series B Preferred Stock in connection with the Private Placement, net of offering costs $11.6 million	0	213,336
Proceeds from issuance of common stock upon stock option exercises	141	109
Proceeds from issuance of stock from employee stock purchase plan	584	356
Net cash provided by financing activities	72,197	213,801
Net increase in cash, cash equivalents and restricted cash	29,433	34,990
Cash, cash equivalents and restricted cash at beginning of period	98,165	53,229
Cash, cash equivalents and restricted cash at end of period	127,598	88,219
Supplemental disclosure of cash flow information:
Cash paid for interest	252
Supplemental disclosure of noncash investing and financing information:
Debt discount included in accrued expenses and other liabilities	3,100
Debt issuance costs included in accounts payable and accrued expenses	236
Offering costs included in accounts payable and accrued expenses	0	49
Series A Preferred Stock [Member]
Supplemental disclosure of noncash investing and financing information:
Conversion of Series Preferred Stock into common shares	2,685
Series B Preferred Stock [Member]
Supplemental disclosure of noncash investing and financing information:
Conversion of Series Preferred Stock into common shares	$ 0	$ 107,980