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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Cash flows from operating activities:    
Net loss $ (71,986) $ (58,348)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization expense 640 599
Stock-based compensation expense 10,008 9,393
Amortization of operating leases, right-of-use assets 498 467
Net amortization (accretion) of premiums (discounts) on marketable securities (955) (1,396)
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets 2,172 (1,102)
Other assets   (2)
Accounts payable 2,141 4,910
Accrued expenses and other current liabilities (8,658) (6,720)
Operating lease liability (376) (330)
Other liabilities 5  
Net cash used in operating activities (66,511) (52,529)
Cash flows from investing activities:    
Purchases of property and equipment (547) (70)
Purchases of marketable securities   (73,014)
Maturities and sales of marketable securities 69,926 74,128
Net cash provided by investing activities 69,379 1,044
Cash flows from financing activities:    
Proceeds from issuance of common stock under ATM, net of issuance costs of $0.7 million 24,250  
Proceeds from issuance of common stock and Series B Preferred Stock in connection with the Private Placement, net of offering costs $11.6 million   213,701
Proceeds from issuance of common stock upon stock option exercises 136 0
Proceeds from issuance of stock from employee stock purchase plan 584 356
Net cash provided by financing activities 24,970 214,057
Net increase in cash, cash equivalents and restricted cash 27,838 162,572
Cash, cash equivalents and restricted cash at beginning of period 98,165 53,229
Cash, cash equivalents and restricted cash at end of period 126,003 215,801
Supplemental disclosure of non-cash investing and financing information:    
Offering costs included in accounts payable and accrued expenses 0 282
Property & equipment included in accounts payable and accrued expenses 79 $ 0
Series A Preferred Stock [Member]    
Supplemental disclosure of non-cash investing and financing information:    
Conversion of Series Preferred Stock into common shares $ 2,435