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Number of development performance milestones.

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Number of development performance milestones to be probable of achievement.

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Number of research performance milestones.

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The percentage of the number of shares of the Company's common stock outstanding on the immediately preceding December 31 which will determine the increase in shares of common stock issued under the Plan.

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Amount of expense recognized from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments), awarded to key employees or individuals. Excludes amount related to plans that cover generally all employees (for example, but not limited to, qualified pension plans).

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Amount of additional cost recognized for award under share-based payment arrangement from occurrence of event accelerating recognition of cost.

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Number of additional shares authorized for issuance under share-based payment arrangement.

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