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Nature of the Business and Basis of Presentation - Additional Information (Detail) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Dec. 31, 2024
Organization, Consolidation and Presentation of Financial Statements [Abstract]      
Net loss $ 71,986 $ 58,348  
Accumulated deficit $ 931,469   $ 859,483