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Condensed Consolidated Statements of Stockholders' Equity - USD ($)
$ in Thousands
Total
Underwritten Public Offering [Member]
Preferred Stock [Member]
Series A Non-Voting Convertible Preferred Stock [Member]
Preferred Stock [Member]
Series B Non-Voting Convertible Preferred Stock [Member]
Common Stock [Member]
Common Stock [Member]
Underwritten Public Offering [Member]
Additional Paid-in Capital [Member]
Additional Paid-in Capital [Member]
Underwritten Public Offering [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Accumulated Deficit [Member]
Beginning Balances at Dec. 31, 2022 $ 255,735   $ 65,830   $ 70   $ 601,153   $ (104) $ (411,214)
Beginning Balances, Shares at Dec. 31, 2022     81,050   69,893,434          
Conversion of preferred stock into common stock     $ (3,520)   $ 1   3,519      
Conversion of preferred stock into common stock, Shares     (4,000)   1,000,000          
Issuance of common stock under Employee Stock Purchase Plan 313           313      
Issuance of common stock under Employee Stock Purchase Plan, Shares         39,228          
Issuance of common stock upon exercise of stock options 132           132      
Issuance of common stock upon exercise of stock options, Shares         14,128          
Unrealized gains (losses) on marketable securities 120               120  
Stock-based compensation expense 5,850           5,850      
Net loss (38,587)                 (38,587)
Ending Balances at Mar. 31, 2023 223,563   $ 62,310   $ 71   610,967   16 (449,801)
Ending Balances, Shares at Mar. 31, 2023     77,050   70,946,790          
Beginning Balances at Dec. 31, 2022 255,735   $ 65,830   $ 70   601,153   (104) (411,214)
Beginning Balances, Shares at Dec. 31, 2022     81,050   69,893,434          
Net loss (82,663)                  
Ending Balances at Jun. 30, 2023 348,428   $ 62,310   $ 85   780,007   (97) (493,877)
Ending Balances, Shares at Jun. 30, 2023     77,050   85,334,165          
Beginning Balances at Mar. 31, 2023 223,563   $ 62,310   $ 71   610,967   16 (449,801)
Beginning Balances, Shares at Mar. 31, 2023     77,050   70,946,790          
Issuance of common stock in underwritten public offering, net of offering costs of 10.7 million   $ 161,789       $ 14   $ 161,775    
Issuance of common stock in underwritten public offering, net of offering costs of 10.7 million, Shares           14,375,000        
Issuance of common stock upon exercise of stock options 102           102      
Issuance of common stock upon exercise of stock options, Shares         12,375          
Unrealized gains (losses) on marketable securities (113)               (113)  
Stock-based compensation expense 7,163           7,163      
Net loss (44,076)                 (44,076)
Ending Balances at Jun. 30, 2023 348,428   $ 62,310   $ 85   780,007   (97) (493,877)
Ending Balances, Shares at Jun. 30, 2023     77,050   85,334,165          
Beginning Balances at Dec. 31, 2023 257,802   $ 60,035   $ 86   801,059   246 (603,624)
Beginning Balances, Shares at Dec. 31, 2023     74,465   86,124,249          
Issuance of Series B Preferred Stock and common stock, net of issuance costs of $11.6 million, in connection with the Private Placement 213,416     $ 87,364 $ 18   126,034      
Issuance of Series B Preferred Stock and common stock, net of issuance costs of $11.6 million, in connection with the Private Placement, Shares       12,280 17,717,997          
Exchange of common stock for Series B Preferred Stock       $ 74,754 $ (8)   (74,746)      
Exchange of common stock for Series B Preferred Stock, Shares       8,300 (8,300,000)          
Issuance of common stock upon exercise of stock options 356           356      
Issuance of common stock upon exercise of stock options, Shares         71,150          
Unrealized gains (losses) on marketable securities (285)               (285)  
Stock-based compensation expense 9,393           9,393      
Net loss (58,348)                 (58,348)
Ending Balances at Mar. 31, 2024 422,334   $ 60,035 $ 162,118 $ 96   862,096   (39) (661,972)
Ending Balances, Shares at Mar. 31, 2024     74,465 20,580 95,613,396          
Beginning Balances at Dec. 31, 2023 257,802   $ 60,035   $ 86   801,059   246 (603,624)
Beginning Balances, Shares at Dec. 31, 2023     74,465   86,124,249          
Net loss (117,298)                  
Ending Balances at Jun. 30, 2024 373,223   $ 60,035 $ 54,085 $ 109   980,108   (192) (720,922)
Ending Balances, Shares at Jun. 30, 2024     74,465 6,868 109,343,224          
Beginning Balances at Mar. 31, 2024 422,334   $ 60,035 $ 162,118 $ 96   862,096   (39) (661,972)
Beginning Balances, Shares at Mar. 31, 2024     74,465 20,580 95,613,396          
Conversion of preferred stock into common stock       $ (107,980) $ 13   107,967      
Conversion of preferred stock into common stock, Shares       (13,712) 13,712,000          
Issuance of common stock upon exercise of stock options 109           109      
Issuance of common stock upon exercise of stock options, Shares         17,828          
Change in estimate on Private Placement issuance costs (129)     $ (53)     (76)      
Unrealized gains (losses) on marketable securities (153)               (153)  
Stock-based compensation expense 10,012           10,012      
Net loss (58,950)                 (58,950)
Ending Balances at Jun. 30, 2024 $ 373,223   $ 60,035 $ 54,085 $ 109   $ 980,108   $ (192) $ (720,922)
Ending Balances, Shares at Jun. 30, 2024     74,465 6,868 109,343,224