Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	Underwritten Public Offering [Member]	ATM [Member]	Preferred Stock [Member]	Preferred Stock [Member] Series A Non-Voting Convertible Preferred Stock [Member]	Common Stock [Member]	Common Stock [Member] Underwritten Public Offering [Member]	Common Stock [Member] ATM [Member]	Additional Paid-in Capital [Member]	Additional Paid-in Capital [Member] Underwritten Public Offering [Member]	Additional Paid-in Capital [Member] ATM [Member]	Accumulated Other Comprehensive (Income) Loss [Member]	Accumulated Deficit [Member]
Beginning Balances at Dec. 31, 2020	$ 234,667			$ 110,881		$ 32			$ 322,454				$ (198,700)
Beginning Balances, Shares at Dec. 31, 2020				132,244		32,347,905
Conversion of preferred stock into common stock					$ (25,481)	$ 8			25,473
Conversion of preferred stock into common stock, Shares					(28,955)	7,238,750
Issuance of common stock for services	260								260
Issuance of common stock for services, Shares						31,683
Issuance of common stock upon exercise of stock options	24								24
Issuance of common stock upon exercise of stock options, Shares						15,758
Issuance of common stock under Employee Stock Purchase Plan	31								31
Issuance of common stock under Employee Stock Purchase Plan, shares						4,497
Issuance of common stock, net of issuance costs			$ 38,006					$ 4			$ 38,002
Issuance of common stock, net of issuance costs, Shares								3,954,900
Issuance of common stock to settle CVR liability	2,043								2,043
Issuance of common stock to settle CVR liability, Shares						212,429
Stock-based compensation expense	11,426								11,426
Net loss	(72,273)												(72,273)
Ending Balances at Dec. 31, 2021	214,184				$ 85,400	$ 44			399,713				(270,973)
Ending Balances, Shares at Dec. 31, 2021					103,289	43,805,922
Conversion of preferred stock into common stock					$ (19,570)	$ 6			19,564
Conversion of preferred stock into common stock, Shares					(22,239)	5,559,750
Issuance of common stock upon exercise of stock options	1,238								1,238
Issuance of common stock upon exercise of stock options, Shares						154,822
Issuance of common stock under Employee Stock Purchase Plan	351								351
Issuance of common stock under Employee Stock Purchase Plan, shares						49,000
Issuance of common stock, net of issuance costs		$ 161,915					$ 18			$ 161,897
Issuance of common stock, net of issuance costs, Shares							17,899,698
Pre-funded warrant exercise	24					$ 2			22
Pre-funded warrant exercise, shares						2,424,242
Unrealized gains (losses) on marketable securities	(104)											$ (104)
Stock-based compensation expense	18,368								18,368
Net loss	(140,241)												(140,241)
Ending Balances at Dec. 31, 2022	255,735				$ 65,830	$ 70			601,153			(104)	(411,214)
Ending Balances, Shares at Dec. 31, 2022					81,050	69,893,434
Conversion of preferred stock into common stock					$ (5,795)	$ 2			5,793
Conversion of preferred stock into common stock, Shares					(6,585)	1,646,250
Issuance of common stock upon exercise of stock options	965								965
Issuance of common stock upon exercise of stock options, Shares						123,687
Issuance of common stock under Employee Stock Purchase Plan	752								752
Issuance of common stock under Employee Stock Purchase Plan, shares						85,878
Issuance of common stock, net of issuance costs		$ 161,789					$ 14			$ 161,775
Issuance of common stock, net of issuance costs, Shares							14,375,000
Unrealized gains (losses) on marketable securities	350											350
Stock-based compensation expense	30,621								30,621
Net loss	(192,410)												(192,410)
Ending Balances at Dec. 31, 2023	$ 257,802				$ 60,035	$ 86			$ 801,059			$ 246	$ (603,624)
Ending Balances, Shares at Dec. 31, 2023					74,465	86,124,249