Condensed Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	Preferred Stock [Member] Series A Non-Voting Convertible Preferred Stock [Member]	Common Stock [Member]	Additional Paid-in Capital [Member]	Accumulated Other Comprehensive Income (Loss) [Member]	Accumulated Deficit [Member]
Beginning Balances at Dec. 31, 2021	$ 214,184	$ 85,400	$ 44	$ 399,713		$ (270,973)
Beginning Balances, Shares at Dec. 31, 2021		103,289	43,805,922
Conversion of Series A non-voting preferred stock into common stock		$ (7,000)	$ 2	6,998
Conversion of Series A non-voting preferred stock into common stock, Shares		(7,955)	1,988,750
Issuance of common stock to settle CVR liability	129			129
Issuance of common stock to settle CVR liability, Shares			18,995
Issuance of common stock for services	9			9
Issuance of common stock for services, Shares			5,599
Stock-based compensation expense	4,175			4,175
Net loss	(30,634)					(30,634)
Ending Balances at Mar. 31, 2022	187,863	$ 78,400	$ 46	411,024		(301,607)
Ending Balances, Shares at Mar. 31, 2022		95,334	45,819,266
Beginning Balances at Dec. 31, 2022	255,735	$ 65,830	$ 70	601,153	$ (104)	(411,214)
Beginning Balances, Shares at Dec. 31, 2022		81,050	69,893,434
Unrealized gains on marketable securities	120				120
Conversion of Series A non-voting preferred stock into common stock		$ (3,520)	$ 1	3,519
Conversion of Series A non-voting preferred stock into common stock, Shares		(4,000)	1,000,000
Issuance of common stock under Employee Stock Purchase Plan	313			313
Issuance of common stock under Employee Stock Purchase Plan, Shares			39,228
Issuance of common stock upon exercise of stock options	132			132
Issuance of common stock upon exercise of stock options, Shares			14,128
Stock-based compensation expense	5,850			5,850
Net loss	(38,587)					(38,587)
Ending Balances at Mar. 31, 2023	$ 223,563	$ 62,310	$ 71	$ 610,967	$ 16	$ (449,801)
Ending Balances, Shares at Mar. 31, 2023		77,050	70,946,790