Accrued Expenses and Other Current Liabilities - Schedule of Accrued Expenses and Other Current Liabilities (Detail) - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Payables and Accruals [Abstract]
Accrued employee compensation and benefits	$ 2,175	$ 6,063
Accrued external research and development expense	6,836	5,898
Accrued external manufacturing costs	3,588	3,741
Accrued professional and consulting services	2,387	1,778
Other	1,015	404
Total	$ 16,001	$ 17,884