Preferred Stock, Series A Non-Voting Convertible Preferred Stock and Common Stock - Additional Information (Detail) - USD ($)				2 Months Ended	12 Months Ended		30 Months Ended
	Jun. 13, 2022	May 06, 2022	Feb. 08, 2021	Mar. 14, 2023	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2022
Class Of Stock [Line Items]
Common stock, Shares authorized					150,000,000	150,000,000	150,000,000
Common stock, Par value					$ 0.001	$ 0.001	$ 0.001
Preferred stock, par value					$ 0.001		$ 0.001
Preferred stock, shares authorized					10,000,000		10,000,000
Pre-funded warrants, purchase price per share					$ 0.01		$ 0.01
Preferred stock, shares outstanding					0		0
Preferred stock, shares issued					0		0
Underwritten Public Offering [Member]
Class Of Stock [Line Items]
Beneficial ownership limitation percentage for conversion of common stock issued and outstanding	9.99%
Exercise of stock options additional shares of common stock	2,730,000
Pre-funded warrants, shares	3,030,302
Underwriters exercise period option	30 days
Offering expenses	$ 400,000
Underwriting discounts and commissions expenses	$ 10,400,000
Pre-funded warrants exercised					2,424,242		2,424,242
Pre-funded warrants remain outstanding					606,060		606,060
Shares of common stock issued and sold	17,899,698
Stock offering price, per share	$ 8.25
Proceeds from issuance of common stock to LPC	$ 161,900,000
SVB Leerink LLC [Member]
Class Of Stock [Line Items]
Shares of common stock issued and sold			3,954,900
Proceeds from issuance of common stock to LPC			$ 38,000,000.0
Guggenheim Securities, LLC [Member]
Class Of Stock [Line Items]
Shares of common stock issued and sold					0
Minimum [Member] | SVB Leerink LLC [Member]
Class Of Stock [Line Items]
Stock offering price, per share			$ 9.25
Maximum [Member]
Class Of Stock [Line Items]
Proceeds from issuance of equity and debt financing		$ 300,000,000.0	$ 200,000,000.0
Maximum [Member] | Underwritten Public Offering [Member]
Class Of Stock [Line Items]
Beneficial ownership limitation percentage for conversion of common stock issued and outstanding	19.99%
Maximum [Member] | SVB Leerink LLC [Member]
Class Of Stock [Line Items]
Stock offering cost			$ 75,000,000.0
Stock offering price, per share			$ 10.30
Maximum [Member] | Guggenheim Securities, LLC [Member]
Class Of Stock [Line Items]
Stock offering cost		$ 75,000,000.0
Common Stock [Member]
Class Of Stock [Line Items]
Conversion of preferred stock into common stock, Shares					5,559,750	7,238,750	20,568,750
Exercise of stock options additional shares of common stock					154,822	15,758
Pre-funded warrants, purchase price per share	$ 0.01
Common stock voting right					Each share of common stock entitles the holder to one vote on all matters submitted to a vote of the Company’s stockholders.
Common Stock [Member] | Subsequent Event [Member]
Class Of Stock [Line Items]
Conversion of preferred stock into common stock, Shares				1,000,000
Common Stock [Member] | Underwritten Public Offering [Member]
Class Of Stock [Line Items]
Pre-funded warrants, purchase price per share	$ 8.24
Series A Preferred Stock [Member]
Class Of Stock [Line Items]
Preferred stock, par value					$ 0.001		$ 0.001
Minimum percentage of originally issued shares remain issued and outstanding					40.00%		40.00%
Convertible preferred stock, common stock issuable upon conversion					250		250
Cumulative amount of shares conversion							82,275
Percentage of preferred stock issued					50.40%		50.40%
Series A Preferred Stock [Member] | Subsequent Event [Member]
Class Of Stock [Line Items]
Cumulative amount of shares conversion				4,000
Series A Preferred Stock [Member] | Minimum [Member]
Class Of Stock [Line Items]
Beneficial ownership limitation percentage for conversion of common stock issued and outstanding					4.90%		4.90%
Series A Preferred Stock [Member] | Maximum [Member]
Class Of Stock [Line Items]
Beneficial ownership limitation percentage for conversion of common stock issued and outstanding					19.90%		19.90%
Undesignated Preferred Stock [Member]
Class Of Stock [Line Items]
Preferred stock, par value					$ 0.001	$ 0.001	$ 0.001
Preferred stock, shares authorized					9,000,000	9,000,000	9,000,000
Preferred stock, shares outstanding					0	0	0
Preferred stock, shares issued					0	0	0
Series A Convertible Preferred Stock [Member]
Class Of Stock [Line Items]
Preferred stock, par value					$ 0.001	$ 0.001	$ 0.001
Preferred stock, shares authorized					1,000,000	1,000,000	1,000,000
Common stock issued upon conversion of preferred stock					20,262,500		20,262,500
Preferred stock, shares outstanding					81,050	103,289	81,050
Preferred stock, shares issued					81,050	103,289	81,050