Condensed Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	Underwritten Public Offering [Member]	Preferred Stock [Member] Series A Non-Voting Convertible Preferred Stock [Member]	Common Stock [Member]	Common Stock [Member] Underwritten Public Offering [Member]	Additional Paid-in Capital [Member]	Additional Paid-in Capital [Member] Underwritten Public Offering [Member]	Accumulated Deficit [Member]
Beginning Balances at Dec. 31, 2020	$ 234,667		$ 110,881	$ 32		$ 322,454		$ (198,700)
Beginning Balances, Shares at Dec. 31, 2020			132,244	32,347,905
Conversion of Series A non-voting preferred stock into common stock			$ (16,200)	$ 5		16,195
Conversion of preferred stock into common stock, Shares			(18,409)	4,602,250
Issuance of common stock to settle CVR liability	2,043					2,043
Issuance of common stock to settle CVR liability, Shares				212,429
Issuance of common stock for services	260					260
Issuance of common stock for services, Shares				31,683
Stock-based compensation expense	1,521					1,521
Net loss	(11,728)							(11,728)
Ending Balances at Mar. 31, 2021	226,763		$ 94,681	$ 37		342,473		(210,428)
Ending Balances, Shares at Mar. 31, 2021			113,835	37,194,267
Beginning Balances at Dec. 31, 2020	234,667		$ 110,881	$ 32		322,454		(198,700)
Beginning Balances, Shares at Dec. 31, 2020			132,244	32,347,905
Net loss	(28,277)
Ending Balances at Jun. 30, 2021	212,804		$ 85,400	$ 40		354,341		(226,977)
Ending Balances, Shares at Jun. 30, 2021			103,289	39,830,767
Beginning Balances at Mar. 31, 2021	226,763		$ 94,681	$ 37		342,473		(210,428)
Beginning Balances, Shares at Mar. 31, 2021			113,835	37,194,267
Conversion of Series A non-voting preferred stock into common stock			$ (9,281)	$ 3		9,278
Conversion of preferred stock into common stock, Shares			(10,546)	2,636,500
Stock-based compensation expense	2,590					2,590
Net loss	(16,549)							(16,549)
Ending Balances at Jun. 30, 2021	212,804		$ 85,400	$ 40		354,341		(226,977)
Ending Balances, Shares at Jun. 30, 2021			103,289	39,830,767
Beginning Balances at Dec. 31, 2021	214,184		$ 85,400	$ 44		399,713		(270,973)
Beginning Balances, Shares at Dec. 31, 2021			103,289	43,805,922
Conversion of Series A non-voting preferred stock into common stock			$ (7,000)	$ 2		6,998
Conversion of preferred stock into common stock, Shares			(7,955)	1,988,750
Issuance of common stock under Employee Stock Purchase Plan	129					129
Issuance of common stock under Employee Stock Purchase Plan, shares				18,995
Issuance of common stock upon exercise of stock options	9					9
Issuance of common stock upon exercise of stock options, Shares				5,599
Stock-based compensation expense	4,175					4,175
Net loss	(30,634)							(30,634)
Ending Balances at Mar. 31, 2022	187,863		$ 78,400	$ 46		411,024		(301,607)
Ending Balances, Shares at Mar. 31, 2022			95,334	45,819,266
Beginning Balances at Dec. 31, 2021	214,184		$ 85,400	$ 44		399,713		(270,973)
Beginning Balances, Shares at Dec. 31, 2021			103,289	43,805,922
Net loss	(65,561)
Ending Balances at Jun. 30, 2022	319,385		$ 71,400	$ 66		584,453		(336,534)
Ending Balances, Shares at Jun. 30, 2022			87,379	65,707,714
Beginning Balances at Mar. 31, 2022	187,863		$ 78,400	$ 46		411,024		(301,607)
Beginning Balances, Shares at Mar. 31, 2022			95,334	45,819,266
Conversion of Series A non-voting preferred stock into common stock			$ (7,000)	$ 2		6,998
Conversion of preferred stock into common stock, Shares			(7,955)	1,988,750
Issuance of common stock and pre-funded warrants in underwritten public offering, net of offering costs		$ 161,915			$ 18		$ 161,897
Issuance of common stock and pre-funded warrants in underwritten public offering, net of offering costs, Shares					17,899,698
Stock-based compensation expense	4,534					4,534
Net loss	(34,927)							(34,927)
Ending Balances at Jun. 30, 2022	$ 319,385		$ 71,400	$ 66		$ 584,453		$ (336,534)
Ending Balances, Shares at Jun. 30, 2022			87,379	65,707,714