Preferred Stock, Series A Non-Voting Convertible Preferred Stock and Common Stock - Additional Information (Detail) - USD ($)				3 Months Ended				6 Months Ended
	Jun. 13, 2022	May 06, 2022	Feb. 08, 2021	Jun. 30, 2022	Mar. 31, 2022	Jun. 30, 2021	Mar. 31, 2021	Jun. 30, 2022	Dec. 31, 2021
Class Of Stock [Line Items]
Common stock, Shares authorized				150,000,000				150,000,000	150,000,000
Common stock, Par value				$ 0.001				$ 0.001	$ 0.001
Preferred stock, par value				$ 0.001				$ 0.001
Preferred stock, shares authorized				10,000,000				10,000,000
Preferred stock, shares outstanding				0				0
Preferred stock, shares issued				0				0
Net proceeds from public offering								$ 162,115,000
Pre-funded warrants, shares				3,030,302				3,030,302
Pre-funded warrants, purchase price per share				$ 0.01				$ 0.01
Underwritten Public Offering [Member]
Class Of Stock [Line Items]
Beneficial ownership limitation percentage for conversion of common stock issued and outstanding	9.99%
Shares of common stock issued and sold	17,899,698
Exercise of stock options additional shares of common stock	2,730,000
Stock offering price, per share	$ 8.25
Proceeds from issuance of common stock to LPC	$ 161,900,000
Underwriting discounts and commissions expenses	10,400,000
Offering expenses	$ 400,000
Pre-funded warrants, shares	3,030,302
Pre-funded warrants exercised				0				0
Underwriters exercise period option	30 days
SVB Leerink LLC [Member]
Class Of Stock [Line Items]
Shares of common stock issued and sold			3,954,900		0			0
Proceeds from issuance of common stock to LPC			$ 38,000,000.0
Guggenheim Securities L L C [Member]
Class Of Stock [Line Items]
Shares of common stock issued and sold								0
Minimum [Member] | SVB Leerink LLC [Member]
Class Of Stock [Line Items]
Stock offering price, per share			$ 9.25
Maximum [Member]
Class Of Stock [Line Items]
Proceeds from issuance of equity and debt financing		$ 300,000,000.0	$ 200,000,000.0
Maximum [Member] | Underwritten Public Offering [Member]
Class Of Stock [Line Items]
Beneficial ownership limitation percentage for conversion of common stock issued and outstanding	19.99%
Maximum [Member] | SVB Leerink LLC [Member]
Class Of Stock [Line Items]
Stock offering cost			$ 75,000,000.0
Stock offering price, per share			$ 10.30
Maximum [Member] | Guggenheim Securities L L C [Member]
Class Of Stock [Line Items]
Stock offering cost		$ 75,000,000.0
Common Stock [Member]
Class Of Stock [Line Items]
Conversion of preferred stock into common stock, Shares				1,988,750	1,988,750	2,636,500	4,602,250
Common stock voting right								Each share of common stock entitles the holder to one vote on all matters submitted to a vote of the Company’s stockholders.
Exercise of stock options additional shares of common stock					5,599
Pre-funded warrants, purchase price per share	$ 0.01
Common Stock [Member] | Underwritten Public Offering [Member]
Class Of Stock [Line Items]
Pre-funded warrants, purchase price per share	$ 8.24
Series A Preferred Stock [Member]
Class Of Stock [Line Items]
Preferred stock, par value				$ 0.001				$ 0.001
Minimum percentage of originally issued shares remain issued and outstanding				40.00%				40.00%
Convertible preferred stock, common stock issuable upon conversion				250				250
Conversion of preferred stock into common stock, Shares								75,946
Percentage of preferred stock issued				46.50%				46.50%
Series A Preferred Stock [Member] | Minimum [Member]
Class Of Stock [Line Items]
Beneficial ownership limitation percentage for conversion of common stock issued and outstanding				4.90%				4.90%
Series A Preferred Stock [Member] | Maximum [Member]
Class Of Stock [Line Items]
Beneficial ownership limitation percentage for conversion of common stock issued and outstanding				19.90%				19.90%
Series A Preferred Stock [Member] | Common Stock [Member]
Class Of Stock [Line Items]
Cumulative amount of shares conversion								18,986,500
Series A Convertible Preferred Stock [Member]
Class Of Stock [Line Items]
Preferred stock, par value				$ 0.001				$ 0.001	$ 0.001
Preferred stock, shares authorized				1,000,000				1,000,000	1,000,000
Preferred stock, shares outstanding				87,379				87,379	103,289
Common stock issued upon conversion of preferred stock				21,844,750				21,844,750
Preferred stock, shares issued				87,379				87,379	103,289
Undesignated Preferred Stock [Member]
Class Of Stock [Line Items]
Preferred stock, par value				$ 0.001				$ 0.001	$ 0.001
Preferred stock, shares authorized				9,000,000				9,000,000	9,000,000
Preferred stock, shares outstanding				0				0	0
Preferred stock, shares issued				0				0	0