X0306 4 2022-06-07 0 0001622229 Cogent Biosciences, Inc. COGT 0001362520 Morris Arlene C/O COGENT BIOSCIENCES, INC. 200 CAMBRIDGE PARK DRIVE, SUITE 2500 CAMBRIDGE MA 02140 1 0 0 0 Stock Option (Right to Buy) 4.59 2022-06-07 4 A 0 30700 0.00 A 2032-06-07 Common Stock 30700 30700 D This annual stock option award was made on the date of the 2022 Annual Meeting of Stockholders pursuant to the company's Non-Employee Director Compensation Program and shall vest in full upon the earlier of the first anniversary of the date of grant or the date of the 2023 Annual Meeting of Stockholders. Exhibit 24 - Power of Attorney /s/ Evan D. Kearns, Attorney-in-Fact 2022-06-09