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Income Taxes - Additional Information (Details) - USD ($)
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Deferred tax assets      
Net operating loss carry forwards $ 27,661,926 $ 24,399,299  
Research and development credit carry forwards 2,666,036 2,291,226  
Stock-based compensation 6,046,848 4,575,617  
Other 650,018 706,745  
Gross deferred tax assets 37,024,828 31,972,887  
Deferred tax liabilities:      
Property and equipment (28,926) (59,524)  
Gross deferred tax liabilities (28,926) (59,524)  
Less valuation allowance (36,995,902) (31,913,363)  
Net deferred tax asset 0 0  
Decrease in deferred tax asset and corresponding valuation allowance     $ 8,700,000
Increase in valuation allowance 5,100,000 11,100,000  
Unrecognized tax benefits      
Unrecognized Tax Benefits $ 0 $ 0  
Reconciliation of income tax expense (benefit) at the statutory federal income tax rate and income taxes      
Federal income tax benefit at statutory rate 21.00% 21.00% 34.00%
State income tax, net of federal benefit 4.20% 6.80% 6.50%
Foreign tax rate differential 0.10% 0.30%  
Nondeductible research and development expenses (4.30%) (2.20%) (5.10%)
Other permanent differences     (0.10%)
Research and development credit benefit 1.00% 1.40% 1.30%
Adjustment of prior years' income taxes (6.60%)    
Rate change from 2017 Tax Cuts and Jobs Act   0.30% (27.30%)
Change in valuation allowance (15.40%) (27.60%) (9.30%)
Effective income tax rate 0.00% 0.00% 0.00%