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Nature of Business and Liquidity - Common Stock and Other (Details) - USD ($)
1 Months Ended 2 Months Ended 3 Months Ended 12 Months Ended 24 Months Ended
Jul. 31, 2018
Mar. 04, 2020
Mar. 04, 2020
Jun. 30, 2019
Mar. 31, 2019
Mar. 31, 2017
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
May 16, 2019
Aug. 30, 2019
Jun. 30, 2017
Sales of Stock                        
Accumulated deficit             $ 150,835,624 $ 117,892,041        
Proceeds from the issuance of common stock, net of issuance costs             $ 45,187,070 $ 29,937,505 $ 57,293,041      
2019 Sales Agreement                        
Sales of Stock                        
Maximum aggregate value of common stock available for offering                     $ 75,000,000  
Shares issued   339,790 353,171       13,381          
Weighted average selling price per share   $ 5.15 $ 5.22       $ 7.00          
Gross proceeds from issuance of common stock   $ 1,700,000 $ 1,800,000       $ 100,000          
Proceeds from the issuance of common stock, net of issuance costs   $ 1,500,000 $ 1,600,000       $ 100,000          
2017 Sales Agreement                        
Sales of Stock                        
Maximum aggregate value of common stock available for offering                       $ 50,000,000
Shares issued       2,082,031 3,439,523       296,594      
Weighted average selling price per share       $ 13.50 $ 5.44       $ 10.74      
Gross proceeds from issuance of common stock       $ 28,100,000 $ 18,700,000       $ 3,200,000 $ 50,000,000    
Proceeds from the issuance of common stock, net of issuance costs       $ 27,000,000 $ 18,100,000       $ 3,000,000      
Follow On Public Offering                        
Sales of Stock                        
Shares issued 4,062,500         3,220,000            
Offering price per share $ 8.00         $ 18.00            
Weighted average selling price per share $ 8.00                      
Gross proceeds from issuance of common stock $ 32,500,000         $ 58,000,000            
Proceeds from the issuance of common stock, net of issuance costs $ 29,900,000         $ 54,200,000