X0306 4 2022-05-20 0 0001620463 Athira Pharma, Inc. ATHA 0001164426 EDELMAN JOSEPH C/O ATHIRA PHARMA, INC. 18706 NORTH CREEK PARKWAY, SUITE 104 BOTHELL WA 98011 1 0 0 0 Stock Option (Right to Buy) 8.93 2022-05-20 4 A 0 13871 0.00 A 2032-05-19 Common Stock 13871 13871 D The shares subject to the option will vest on the earlier of (i) May 20, 2023, or (ii) the day immediately before the date of the next annual meeting of the Issuer's stockholders that occurs after May 20, 2022. The option reported was granted pursuant to the terms of the Issuer's outside director compensation policy. /s/ Glenna Mileson, attorney-in-fact on behalf of Joseph Edelman 2022-05-27