X0206 3 2021-07-22 0 0001619856 Caribou Biosciences, Inc. CRBU 0001231321 MCCLUNG BARBARA G C/O CARIBOU BIOSCIENCES, INC. 2929 7TH STREET, SUITE 105 BERKELEY CA 94710 0 1 0 0 See Remarks Common Stock 333626 D Stock Option (Right to Buy) 2.68 2028-06-11 Common Stock 132 D Stock Option (Right to Buy) 2.68 2029-09-30 Common Stock 90127 D Stock Option (Right to Buy) 4.11 2031-03-29 Common Stock 231914 D The shares subject to this option have vested or will vest in equal monthly installments until the option is fully vested on June 12, 2022, subject to the reporting person's continued service to the Issuer thorough the applicable vesting date. The shares subject to this option have vested or will vest in equal monthly installments until the option is fully vested on October 1, 2023, subject to the reporting person's continued service to the Issuer thorough the applicable vesting date. 1/4th of the shares subject to this option will vest on March 2, 2022 and an additional 1/48th of the aggregate number of shares subject to the option will vest on the corresponding day of each month thereafter, subject to the reporting person's continued service to the Issuer thorough the applicable vesting date. Chief Legal Officer and Corporate Secretary Exhibit 24 - Power of Attorney. /s/ Barbara G. McClung 2021-07-22