X0206 3 2021-07-22 0 0001619856 Caribou Biosciences, Inc. CRBU 0001670579 Haurwitz Rachel E. C/O CARIBOU BIOSCIENCES, INC. 2929 7TH STREET, SUITE 105 BERKELEY CA 94710 1 1 0 0 See Remarks Common Stock 3349395 D Stock Option (Right to Buy) 2.95 2023-06-11 Common Stock 136350 D Stock Option (Right to Buy) 4.11 2031-03-29 Common Stock 437201 D 1/4th of the shares subject to this option vested on June 12, 2019 and an additional 1/48th of the aggregate number of shares subject to the option have vested or will vest on the corresponding day of each month thereafter, subject to the reporting person's continued service to the Issuer thorough the applicable vesting date. 1/4th of the shares subject to this option will vest on March 2, 2022 and an additional 1/48th of the aggregate number of shares subject to the option will vest on the corresponding day of each month thereafter, subject to the reporting person's continued service to the Issuer thorough the applicable vesting date. President and Chief Executive Officer Exhibit 24 - Power of Attorney. /s/ Rachel E. Haurwitz 2021-07-22