Condensed Consolidated Statements of Cash Flows $ in Thousands	9 Months Ended
	Sep. 30, 2016 USD ($)	Sep. 30, 2015 USD ($)
Operating activities
Net loss	$ (36,521)	$ (55,162)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization of property and equipment	1,212	1,251
Amortization of financing costs	4,396	3,299
Noncash interest expense	6,206	9,083
Share-based compensation expense	3,365	4,596
Costs associated with aborted 2015 IPO		3,978
Change in fair value of derivative liabilities	662	(443)
Gain on sale of property and equipment	(121)
Changes in:
Accounts receivable	(187)	(810)
Other receivables	367	(156)
Inventories	665	(903)
Deferred cost of goods sold	(4)	(65)
Prepaid expense and other current assets	(89)	552
Other assets	126	9
Accounts payable	(4,535)	3,555
Accrued expense	451	283
Deferred revenue	73	206
Deferred rent liability	(53)	(39)
Net cash used in operating activities	(23,987)	(30,766)
Investing activities
Proceeds from sale of property and equipment	121
Acquisition of property and equipment	(171)	(921)
Net cash used in investing activities	(50)	(921)
Financing activities
Repayment of capital lease	(26)	(115)
Investor capital contributions		17,982
Proceeds from issuance of private company Series AB Preferred Stock	5,819	3,016
Proceeds from issuance of common stock	25,395
Costs associated with investor capital contributions		(173)
Debt restructuring costs	(355)
Offering costs	(1,431)	(2,418)
Proceeds from exercise of warrants by a related party	7,375
Net cash provided by financing activities	36,777	18,292
Net (decrease)/ increase in cash and cash equivalents	12,740	(13,395)
Cash and cash equivalents-beginning of period	2,789	20,944
Cash and cash equivalents-end of period	15,529	7,549
Supplemental disclosures of cash flow information
Interest paid	0	$ 0
Reclassification of derivative liability upon exercise of warrants	1,557
Cancellation of derivative liability	3,036
Issuance of derivative liabilities for PPO warrants	226
Conversion of interest and fees and write off of remaining debt discounts	17,934
Issuance of Series AB Preferred Stock warrants	$ 4,000