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GENERAL - EXCLUSIVE LICENSE AND SUPPLY AGREEMENT (Details) - USD ($)
$ / shares in Units, $ in Thousands
Apr. 29, 2018
Jun. 28, 2015
Cardiome | Collaboration    
Exclusive License and Supply Agreement    
Upfront payment provided for per license agreement   $ 3,000
Aggregate maximum milestone payments to be achieved per agreement   $ 9,250
Scaling royalty percentage, low end of range   low teens
Scaling royalty percentage, high end of range   mid-teens
United Therapeutics | Steady Med    
Exclusive License and Supply Agreement    
Transaction value $ 216,000  
Contingent consideration $ 75,000  
Acquisition share price $ 4.46  
Additional acquisition share price contingent upon commercialization of steadyMed's Trevyent Product 2.63  
Maximum exercise price of options to receive consideration 7.09  
Right to receive consideration for each outstanding warrant issued pursuant to 2017 subscription agreement 2.33  
Right to receive consideration for each outstanding warrant issued pursuant to 2016 subscription agreement $ 2.71