Exhibit 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We consent to the incorporation by reference in Registration Statement Nos. 333-234769, 333-232303, 333-231126, 333-230191, and 333-223731 on Form S-3 and Registration Statement Nos. 333-252516, 333-238228, 333-237126, 333-237119, 333-231993, 333-231991, 333-226517 and 333-225366 on Form S-8 of our report dated March 4, 2021, relating to the financial statements of Evofem Biosciences, Inc. appearing in this Annual Report on Form 10-K for the year ended December 31, 2020.

/s/ DELOITTE & TOUCHE LLP

San Diego, California

March 4, 2021

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