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    <periodOfReport>2021-12-15</periodOfReport>

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    <issuer>
        <issuerCik>0001618732</issuerCik>
        <issuerName>Nutanix, Inc.</issuerName>
        <issuerTradingSymbol>NTNX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001483009</rptOwnerCik>
            <rptOwnerName>RAMASWAMI RAJIV</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O NUTANIX, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>1740 TECHNOLOGY DR., STE 150</rptOwnerStreet2>
            <rptOwnerCity>SAN JOSE</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>95110</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>President and CEO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

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        <derivativeTransaction>
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                    <value>129418</value>
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    <footnotes>
        <footnote id="F1">Includes shares acquired under the Nutanix, Inc. Employee Stock Purchase Plan on September 20, 2021.</footnote>
        <footnote id="F2">Each Restricted Stock Unit, or RSU, represents a contingent right to receive one share of the Issuer's Class A common stock.</footnote>
        <footnote id="F3">The RSUs vested as to 25% of the underlying shares on December 15, 2021, with 1/16th of the remaining shares to vest quarterly thereafter subject to the Reporting Person continuing to provide service to the Issuer through each vesting date.</footnote>
        <footnote id="F4">As previously reported, on December 9, 2020, the Reporting Person was granted a target number of 703,117 performance-based RSUs (&quot;PRSUs&quot;) subject to two stock price milestones. 133% of the target number of PRSUs became eligible to vest upon achievement of both milestones. The eligible PRSUs vested as to 25% of the underlying shares on December 15, 2021, with 1/16th of the remaining shares to vest quarterly thereafter, subject to the Reporting Person continuing to provide service to the Issuer through each vesting date.</footnote>
        <footnote id="F5">The RSUs vest in 16 equal quarterly installments, with the first of such quarterly installments having vested on December 15, 2021, subject to the Reporting Person continuing to provide service to the Issuer through each vesting date.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Hae Cheong Chang, Attorney in Fact</signatureName>
        <signatureDate>2021-12-17</signatureDate>
    </ownerSignature>
</ownershipDocument>
