Consolidated Schedule of Investments  (unaudited) September 30, 2020 BlackRock Science and Technology Trust (BST) (Percentages shown are based on Net Assets)

Security	Shares		Value
Common Stocks
Automobiles — 1.2%
Tesla, Inc.(a)(b)		29,130	$	12,497,061
Banks — 1.1%
Klarna Holdings AB, (Acquired 08/07/19, Cost: $7,971,978)(c)(d)		26,430		11,167,128
Diversified Consumer Services(a)(b) — 1.6%
Chegg, Inc.		120,357		8,598,304
TAL Education Group, ADR		109,038		8,291,250
				16,889,554
Diversified Financial Services — 0.4%
TransferWise, (Acquired 06/03/19, Cost: $2,471,478)(c)(d)		27,945		3,499,552
Diversified Telecommunication Services — 0.9%
Bandwidth, Inc., Class A(a)(b)		50,261		8,774,063
Electronic Equipment, Instruments & Components — 0.7%
Samsung SDI Co. Ltd.		18,473		6,824,265
Entertainment(a) — 3.6%
Activision Blizzard, Inc.		108,779		8,805,660
NetEase, Inc., ADR		15,079		6,855,969
Netflix, Inc.(b)		13,669		6,834,910
Roku, Inc.(b)		48,457		9,148,682
Tencent Music Entertainment Group, ADR(b)		387,074		5,717,083
				37,362,304
Health Care Technology(b) — 1.6%
Ping An Healthcare and Technology Co. Ltd.(e)		488,078		6,297,598
Teladoc Health, Inc.(a)		48,402		10,611,655
				16,909,253
Interactive Media & Services — 10.1%
Alphabet, Inc., Class A(a)(b)		15,503		22,721,197
Facebook, Inc., Class A(a)(b)		46,152		12,087,209
Kakao Corp.		47,217		14,682,294
Snap, Inc., Class A(a)(b)		317,203		8,282,170
Tencent Holdings Ltd.		385,400		26,031,215
Yandex NV, Class A(a)(b)		160,240		10,455,660
ZoomInfo Technologies, Inc., Class A(a)(b)		241,571		10,385,137
				104,644,882
Internet & Direct Marketing Retail — 10.9%
Alibaba Group Holding Ltd., ADR(a)(b)		114,300		33,601,914
Amazon.com, Inc.(a)(b)		11,136		35,064,257
Delivery Hero SE(b)(e)		98,747		11,330,157
Ensogo Ltd.(b)(c)		173,282		1
Jasper Infotech Private Ltd., (Acquired 08/08/15, Cost: $1,998,435)(c)(d)		1,054		253,888
Meituan Dianping, Class B(b)		576,096		18,147,763
MercadoLibre, Inc.(a)(b)		13,361		14,463,015
				112,860,995
IT Services — 19.0%
Adyen NV(b)(e)		5,298		9,772,071
GMO Payment Gateway, Inc.		74,300		7,959,208
Mastercard, Inc., Class A(a)		74,075		25,049,943
MongoDB, Inc.(a)(b)		29,473		6,823,294
Okta, Inc.(a)(b)		65,832		14,078,173
Pagseguro Digital Ltd., Class A(a)(b)		145,648		5,492,386
PayPal Holdings, Inc.(a)(b)		106,075		20,899,957

Security	Shares		Value
IT Services (continued)
Shopify, Inc., Class A(a)(b)		19,006	$	19,442,568
Snowflake, Inc., Class A(a)(b)		8,644		2,169,644
Square, Inc., Class A(a)(b)		144,512		23,490,425
StoneCo Ltd., Class A(a)(b)		167,534		8,860,873
TRAX Ltd., (Acquired 09/12/19, Cost: $4,000,012)(c)(d)		106,667		5,990,419
Trumid Holdings LLC, Class J-A(c)		5,038		1,999,784
Trumid Holdings LLC, Class J-B(c)		5,038		1,999,784
Twilio, Inc., Class A(a)(b)		89,272		22,058,218
Visa, Inc., Class A(a)		102,176		20,432,135
				196,518,882
Semiconductors & Semiconductor Equipment — 12.7%
Advanced Micro Devices, Inc.(a)(b)		236,104		19,358,167
ASML Holding NV		35,871		13,249,774
Cree, Inc.(a)(b)		120,271		7,666,074
Inphi Corp.(a)(b)		89,383		10,033,242
Lam Research Corp.(a)		36,164		11,997,407
Marvell Technology Group Ltd.(a)		343,206		13,625,278
Monolithic Power Systems, Inc.(a)		33,117		9,259,844
Renesas Electronics Corp.(b)		1,084,400		7,959,106
Skyworks Solutions, Inc.(a)		47,575		6,922,163
SOITEC(b)		74,283		10,696,425
STMicroelectronics NV		293,649		9,006,213
Taiwan Semiconductor Manufacturing Co. Ltd., ADR(a)		136,608		11,074,811
				130,848,504
Software — 24.4%
Adobe, Inc.(a)(b)		42,101		20,647,594
Altium Ltd.		259,235		6,740,442
Atlassian Corp. PLC, Class A(a)(b)		49,062		8,918,981
Autodesk, Inc.(a)(b)		40,617		9,382,933
Avalara, Inc.(a)(b)		81,798		10,416,157
Cadence Design Systems, Inc.(a)(b)		77,759		8,291,442
Coupa Software, Inc.(a)(b)		45,108		12,370,418
Crowdstrike Holdings, Inc., Class A(a)(b)		56,369		7,740,591
Databricks, Inc., (Acquired 07/24/20, Cost: $960,476)(c)(d)		19,999		959,952
Elastic NV(a)(b)		56,525		6,098,482
Fair Isaac Corp.(a)(b)		12,734		5,416,789
Intuit, Inc.(a)		22,130		7,219,027
Kingdee International Software Group Co. Ltd.(b)		4,123,000		10,754,034
Microsoft Corp.(a)		199,157		41,888,692
Online Ventures Pty Ltd., (Acquired 01/21/20, Cost: $6,160,136)(c)(d)		53,642		5,877,655
Paycom Software, Inc.(a)(b)		20,090		6,254,017
RingCentral, Inc., Class A(a)(b)		41,312		11,344,688
salesforce.com, Inc.(a)(b)		43,202		10,857,527
ServiceNow, Inc.(a)(b)		28,435		13,790,975
TeamViewer AG(b)(e)		169,717		8,370,414
Think & Learn Private Ltd., (Acquired 09/30/20, Cost: $1,524,948)(c)(d)		997		1,515,194
Unity Software, Inc.(b)		82,957		7,240,487
Xero Ltd.(b)		112,503		8,206,537
Zoom Video Communications, Inc., Class A(a)(b)		20,211		9,501,393
Zscaler, Inc.(a)(b)		91,823		12,918,578
				252,722,999

CONSOLIDATED SCHEDULE OF INVESTMENTS 1

Consolidated Schedule of Investments  (unaudited) (continued) September 30, 2020 BlackRock Science and Technology Trust (BST) (Percentages shown are based on Net Assets)

Security	Shares		Value
Technology Hardware, Storage & Peripherals — 4.3%
Apple, Inc.(a)		387,449	$	44,870,469
Total Common Stocks — 92.5% (Cost: $310,592,564)				956,389,911
Preferred Securities
Preferred Stocks — 8.3%(c)(d)
Diversified Financial Services — 0.3%
TransferWise
Series A, (Acquired 06/03/19, Cost: $1,004,242)		11,355		1,421,987
Series B, (Acquired 06/03/19, Cost: $288,407)		3,261		408,375
Series C, (Acquired 06/03/19, Cost: $161,315)		1,824		228,419
Series D, (Acquired 06/03/19, Cost: $44,579)		504		63,116
Series E, (Acquired 06/03/19, Cost: $4,688)		53		6,637
TransferWise (Seed Preferred), (Acquired 06/03/19, Cost: $849,295)		9,603		1,202,584
				3,331,118
Electronic Equipment, Instruments & Components — 0.5%
Credo Technology Group Holding Ltd., Series D, (Acquired 03/20/20, Cost: $5,000,001)		1,001,382		4,996,896
Food Products — 0.3%
Farmer’s Business Network, Inc, Series F, (Acquired 07/31/20, Cost: $2,999,886)		90,750		3,000,195
Internet & Direct Marketing Retail — 0.5%
Postmates, Inc., Series F, (Acquired 01/08/19, Cost: $3,130,002)		392,275		4,985,815
Road & Rail — 1.7%
Ant Financial, Series C, (Acquired 05/18/18, Cost: $6,492,863)		1,157,373		9,525,180
FlixMobility GmbH, Series F, (Acquired 07/26/19, Cost: $5,482,937)		275		2,826,227
Xiaoju Kuaizhi, Inc., Series A-17, (Acquired 07/28/15, Cost: $3,016,964)		110,003		5,387,947
				17,739,354
Semiconductors & Semiconductor Equipment — 2.2%
Innovium, Inc., Series E, (Acquired 08/21/19, Cost: $3,000,003)		353,478		3,029,307
Innovium, Inc., Series F, (Acquired 06/10/20, Cost: $2,999,996)		296,062		2,913,250
Nuvia Inc, Series B, (Acquired 09/17/20, Cost: $2,999,998)		935,352		3,000,001
Psiquantum Corp., Series C, (Acquired 09/09/19, Cost: $3,200,234)		690,003		3,187,814
SambaNova Systems, Inc., Series C, (Acquired 02/20/20, Cost: $9,972,126)		187,300		10,398,896
				22,529,268
Software — 2.8%
Avidxchange, Inc., (Acquired 07/29/20, Cost: $2,022,088)		41,257		2,022,005
C3 AI, Inc., Series H, (Acquired 08/14/19, Cost: $7,129,478)		1,415,000		7,513,650
Databricks, Inc., Series F, (Acquired 10/22/19, Cost: $3,999,999)		93,135		4,470,480

Security	Shares		Value
Software (continued)
GitLab, Inc., Series E, (Acquired 09/10/19, Cost: $2,915,501)		156,500	$	3,341,275
Think & Learn Private Ltd., Series F, (Acquired 09/30/20, Cost: $3,052,975)		1,054		3,043,458
Unqork, Inc, Series C, (Acquired 09/18/20, Cost: $1,303,260)		1,190		1,303,260
Unqork, Inc., Series B, (Acquired 09/19/19, Cost: $3,198,416)		7,027		7,695,830
				29,389,958
Total Preferred Stocks — 8.3%				85,972,604
Total Preferred Securities — 8.3% (Cost: $74,269,253)				85,972,604
Warrants
IT Services — 0.0%
TRAX Ltd., (Acquired 09/12/19, Cost: $0)(c)(d)		17,065		180,718
Total Warrants — 0.0% (Cost: $ — )				180,718
Total Long-Term Investments — 100.8% (Cost: $384,861,817)				1,042,543,233
Short-Term Securities
Money Market Funds — 0.2%
BlackRock Liquidity Funds, T-Fund, Institutional Class, 0.02%(f)(g)		2,316,076		2,316,076
Total Short-Term Securities — 0.2% (Cost: $2,316,076)				2,316,076
Total Investments Before Options Written — 101.0% (Cost: $387,177,893)				1,044,859,309
Options Written — (1.4)% (Premiums Received: $(13,668,303))				(13,850,487	)
Total Investments, Net of Options Written — 99.6% (Cost: $373,509,590)				1,031,008,822
Other Assets Less Liabilities — 0.4%				3,646,619
Net Assets — 100.0%			$	1,034,655,441

^(a)  All or a portion of the security has been pledged and/or segregated as collateral in connection with outstanding exchange-traded options written.

^(b)  Non-income producing security.

^(c)  Security is valued using significant unobservable inputs and is classified as Level 3 in the fair value hierarchy.

^(d)  Restricted security as to resale, excluding 144A securities. The Trust held restricted securities with a current value of $115,417,110, representing 11.16% of its net assets as of period end, and an original cost of $99,356,716.

^(e)  Security exempt from registration pursuant to Rule 144A under the Securities Act of 1933, as amended. These securities may be resold in transactions exempt from registration to qualified institutional investors.

^(f)  Affiliate of the Trust.

^(g)  Annualized 7-day yield as of period end.

2

Consolidated Schedule of Investments  (unaudited) (continued) September 30, 2020 BlackRock Science and Technology Trust (BST)

Affiliates

Investments in issuers considered to be affiliate(s) of the Trust during the period ended September 30, 2020, for purposes of Section 2(a)(3) of the Investment Company Act of 1940, as amended, were as follows:

Affiliated Issuer	Value at 12/31/19		Purchases at Cost			Proceeds from Sales			Net Realized Gain (Loss)			Change in Unrealized Appreciation (Depreciation)		Value at 09/30/20		Shares Held at 09/30/20		Income			Capital Gain Distributions from Underlying Funds
BlackRock Liquidity Funds, T-Fund, Institutional Class	$	8,881,516	$	—		$	(6,565,440	)(a)	$	—		$	—	$	2,316,076		2,316,076	$	25,712		$	—
SL Liquidity Series, LLC, Money Market Series		—		495	(a)		—			(495	)		—		—		—		24,063	(b)		—
									$	(495	)	$	—	$	2,316,076			$	49,775		$	—

^(a) Represents net amount purchased (sold).

^(b) All or a portion represents securities lending income earned from the reinvestment of cash collateral from loaned securities, net of fees and collateral investment expenses, and other payments to and from borrowers of securities.

For Trust compliance purposes, the Trust’s industry classifications refer to one or more of the industry sub-classifications used by one or more widely recognized market indexes or rating group indexes, and/or as defined by the investment adviser. These definitions may not apply for purposes of this report, which may combine such industry sub-classifications for reporting ease.

Derivative Financial Instruments Outstanding as of Period End

Exchange-Traded Options Written

Description	Number of Contracts		Expiration Date		Exercise Price		Notional Amount (000)		Value
Call
Alibaba Group Holding Ltd., ADR		26		10/02/20	USD	275.00	USD	764	$	(49,920	)
Amazon.com, Inc.		14		10/02/20	USD	3,250.00	USD	4,408		(8,365	)
Atlassian Corp. PLC, Class A		6		10/02/20	USD	175.00	USD	109		(4,380	)
Autodesk, Inc.		68		10/02/20	USD	260.00	USD	1,571		(340	)
Marvell Technology Group Ltd.		207		10/02/20	USD	38.50	USD	822		(28,876	)
RingCentral, Inc., Class A		17		10/02/20	USD	300.00	USD	467		(765	)
ServiceNow, Inc.		40		10/02/20	USD	460.00	USD	1,940		(103,400	)
Snap, Inc., Class A		136		10/02/20	USD	25.00	USD	355		(15,844	)
Square, Inc., Class A		90		10/02/20	USD	172.50	USD	1,463		(4,635	)
Taiwan Semiconductor Manufacturing Co. Ltd., ADR		212		10/02/20	USD	78.50	USD	1,719		(60,950	)
Teladoc Health, Inc.		78		10/02/20	USD	230.00	USD	1,710		(6,435	)
Tesla, Inc.		55		10/02/20	USD	360.00	USD	2,360		(380,600	)
Twilio, Inc., Class A		68		10/02/20	USD	255.00	USD	1,680		(18,190	)
Visa, Inc., Class A		40		10/02/20	USD	202.50	USD	800		(2,600	)
Yandex NV, Class A		35		10/02/20	USD	67.00	USD	228		(1,050	)
Adobe, Inc.		35		10/09/20	USD	495.00	USD	1,716		(30,625	)
Advanced Micro Devices, Inc.		30		10/09/20	USD	105.00	USD	246		(420	)
Alphabet, Inc., Class A		15		10/09/20	USD	1,635.00	USD	2,198		(1,575	)
Amazon.com, Inc.		14		10/09/20	USD	3,450.00	USD	4,408		(7,875	)
Apple, Inc.		232		10/09/20	USD	132.50	USD	2,687		(1,624	)
Atlassian Corp. PLC, Class A		159		10/09/20	USD	180.00	USD	2,890		(89,835	)
Cree, Inc.		95		10/09/20	USD	67.00	USD	606		(6,175	)
Crowdstrike Holdings, Inc., Class A		83		10/09/20	USD	131.00	USD	1,140		(73,040	)
Intuit, Inc.		32		10/09/20	USD	347.50	USD	1,044		(1,760	)
Lam Research Corp.		27		10/09/20	USD	327.50	USD	896		(30,780	)
Marvell Technology Group Ltd.		376		10/09/20	USD	39.50	USD	1,493		(41,924	)
Mastercard, Inc., Class A		39		10/09/20	USD	370.00	USD	1,319		(2,925	)
Microsoft Corp.		69		10/09/20	USD	232.50	USD	1,451		(518	)
Microsoft Corp.		76		10/09/20	USD	212.50	USD	1,599		(20,254	)
MongoDB, Inc.		49		10/09/20	USD	252.50	USD	1,134		(7,473	)
Netflix, Inc.		17		10/09/20	USD	550.00	USD	850		(2,720	)
Okta, Inc.		17		10/09/20	USD	227.50	USD	364		(2,661	)
PayPal Holdings, Inc.		148		10/09/20	USD	205.00	USD	2,916		(25,974	)
Shopify, Inc., Class A		12		10/09/20	USD	1,090.00	USD	1,228		(12,840	)
Snap, Inc., Class A		265		10/09/20	USD	24.50	USD	692		(49,157	)
Snap, Inc., Class A		121		10/09/20	USD	25.00	USD	316		(17,484	)
Square, Inc., Class A		200		10/09/20	USD	165.00	USD	3,251		(93,500	)

CONSOLIDATED SCHEDULE OF INVESTMENTS 3

Consolidated Schedule of Investments  (unaudited) (continued) September 30, 2020 BlackRock Science and Technology Trust (BST)

Exchange-Traded Options Written (continued)

Description	Number of Contracts		Expiration Date		Exercise Price		Notional Amount (000)		Value
Call (continued)
StoneCo Ltd., Class A		169		10/09/20	USD	57.00	USD	894	$	(4,648	)
Taiwan Semiconductor Manufacturing Co. Ltd., ADR		74		10/09/20	USD	85.00	USD	600		(3,515	)
Teladoc Health, Inc.		98		10/09/20	USD	210.00	USD	2,149		(134,260	)
Tesla, Inc.		13		10/09/20	USD	475.00	USD	558		(9,458	)
Twilio, Inc., Class A		45		10/09/20	USD	265.00	USD	1,112		(15,300	)
Zscaler, Inc.		76		10/09/20	USD	160.00	USD	1,069		(2,812	)
Activision Blizzard, Inc.		78		10/16/20	USD	82.50	USD	631		(12,441	)
Adobe, Inc.		30		10/16/20	USD	530.00	USD	1,471		(8,205	)
Advanced Micro Devices, Inc.		158		10/16/20	USD	87.50	USD	1,295		(24,727	)
Alibaba Group Holding Ltd., ADR		58		10/16/20	USD	285.00	USD	1,705		(83,810	)
Amazon.com, Inc.		12		10/16/20	USD	3,400.00	USD	3,778		(29,970	)
Apple, Inc.		232		10/16/20	USD	120.00	USD	2,687		(50,924	)
Atlassian Corp. PLC, Class A		4		10/16/20	USD	180.00	USD	73		(2,960	)
Avalara, Inc.		135		10/16/20	USD	130.00	USD	1,719		(58,050	)
Bandwidth, Inc., Class A		90		10/16/20	USD	150.00	USD	1,571		(233,100	)
Cadence Design Systems, Inc.		131		10/16/20	USD	109.67	USD	1,397		(26,467	)
Chegg, Inc.		209		10/16/20	USD	85.00	USD	1,493		(3,135	)
Cree, Inc.		226		10/16/20	USD	67.50	USD	1,441		(18,645	)
Crowdstrike Holdings, Inc., Class A		35		10/16/20	USD	120.00	USD	481		(65,537	)
Elastic NV		99		10/16/20	USD	105.00	USD	1,068		(65,340	)
Facebook, Inc., Class A		87		10/16/20	USD	260.00	USD	2,279		(77,212	)
Fair Isaac Corp.		21		10/16/20	USD	440.00	USD	893		(15,750	)
Inphi Corp.		151		10/16/20	USD	120.00	USD	1,695		(20,007	)
Intuit, Inc.		11		10/16/20	USD	360.00	USD	359		(495	)
Lam Research Corp.		30		10/16/20	USD	335.00	USD	995		(29,700	)
Mastercard, Inc., Class A		38		10/16/20	USD	340.00	USD	1,285		(25,840	)
Microsoft Corp.		5		10/16/20	USD	230.00	USD	105		(213	)
MongoDB, Inc.		58		10/16/20	USD	240.00	USD	1,343		(37,700	)
Monolithic Power Systems, Inc.		58		10/16/20	USD	281.00	USD	1,622		(57,689	)
Netflix, Inc.		15		10/16/20	USD	520.00	USD	750		(13,725	)
Pagseguro Digital Ltd., Class A		291		10/16/20	USD	40.00	USD	1,097		(20,370	)
Roku, Inc.		117		10/16/20	USD	175.00	USD	2,209		(206,505	)
salesforce.com, Inc.		75		10/16/20	USD	250.00	USD	1,885		(65,250	)
ServiceNow, Inc.		17		10/16/20	USD	480.00	USD	824		(31,960	)
Shopify, Inc., Class A		40		10/16/20	USD	975.00	USD	4,092		(291,400	)
Snap, Inc., Class A		60		10/16/20	USD	25.00	USD	157		(10,170	)
Snap, Inc., Class A		264		10/16/20	USD	24.00	USD	689		(64,284	)
Taiwan Semiconductor Manufacturing Co. Ltd., ADR		168		10/16/20	USD	80.00	USD	1,362		(59,640	)
TAL Education Group, ADR		194		10/16/20	USD	80.00	USD	1,475		(19,400	)
Teladoc Health, Inc.		98		10/16/20	USD	220.00	USD	2,149		(103,390	)
Tencent Music Entertainment Group, ADR		656		10/16/20	USD	18.00	USD	969		(2,624	)
Tesla, Inc.		55		10/16/20	USD	403.00	USD	2,360		(232,650	)
Tesla, Inc.		12		10/16/20	USD	500.00	USD	515		(9,270	)
Twilio, Inc., Class A		92		10/16/20	USD	250.00	USD	2,273		(96,370	)
Unity Software, Inc.		145		10/16/20	USD	100.00	USD	1,266		(47,850	)
Unity Software, Inc.		145		10/16/20	USD	90.00	USD	1,266		(87,000	)
Visa, Inc., Class A		65		10/16/20	USD	210.00	USD	1,300		(6,240	)
Zoom Video Communications, Inc., Class A		27		10/16/20	USD	430.00	USD	1,269		(142,965	)
ZoomInfo Technologies, Inc., Class A		423		10/16/20	USD	45.00	USD	1,818		(61,335	)
Activision Blizzard, Inc.		77		10/23/20	USD	81.50	USD	623		(18,711	)
Adobe, Inc.		35		10/23/20	USD	485.00	USD	1,716		(76,125	)
Advanced Micro Devices, Inc.		356		10/23/20	USD	92.00	USD	2,919		(52,510	)
Alibaba Group Holding Ltd., ADR		130		10/23/20	USD	290.00	USD	3,822		(172,575	)
Alphabet, Inc., Class A		14		10/23/20	USD	1,535.00	USD	2,052		(25,130	)
Alphabet, Inc., Class A		16		10/23/20	USD	1,510.00	USD	2,345		(42,560	)
Apple, Inc.		124		10/23/20	USD	121.00	USD	1,436		(32,426	)
Autodesk, Inc.		33		10/23/20	USD	252.50	USD	762		(5,874	)
Coupa Software, Inc.		83		10/23/20	USD	262.50	USD	2,276		(177,205	)
Cree, Inc.		99		10/23/20	USD	64.00	USD	631		(33,165	)
Facebook, Inc., Class A		11		10/23/20	USD	270.00	USD	288		(6,683	)
Intuit, Inc.		32		10/23/20	USD	320.00	USD	1,044		(44,800	)
Marvell Technology Group Ltd.		34		10/23/20	USD	41.50	USD	135		(2,601	)

4

Consolidated Schedule of Investments  (unaudited) (continued) September 30, 2020 BlackRock Science and Technology Trust (BST)

Exchange-Traded Options Written (continued)

Description	Number of Contracts		Expiration Date		Exercise Price		Notional Amount (000)		Value
Call (continued)
Mastercard, Inc., Class A		40		10/23/20	USD	335.00	USD	1,353	$	(46,900	)
Microsoft Corp.		76		10/23/20	USD	212.50	USD	1,599		(43,130	)
MongoDB, Inc.		6		10/23/20	USD	235.00	USD	139		(6,420	)
Okta, Inc.		17		10/23/20	USD	222.50	USD	364		(11,178	)
RingCentral, Inc., Class A		18		10/23/20	USD	287.50	USD	494		(14,130	)
RingCentral, Inc., Class A		55		10/23/20	USD	275.00	USD	1,510		(75,625	)
Roku, Inc.		18		10/23/20	USD	175.00	USD	340		(35,190	)
salesforce.com, Inc.		11		10/23/20	USD	270.00	USD	276		(4,307	)
Shopify, Inc., Class A		41		10/23/20	USD	1,030.00	USD	4,194		(205,000	)
Skyworks Solutions, Inc.		70		10/23/20	USD	141.00	USD	1,018		(60,200	)
Snap, Inc., Class A		64		10/23/20	USD	25.50	USD	167		(14,112	)
Taiwan Semiconductor Manufacturing Co. Ltd., ADR		20		10/23/20	USD	83.00	USD	162		(5,420	)
Teladoc Health, Inc.		49		10/23/20	USD	220.00	USD	1,074		(62,965	)
Teladoc Health, Inc.		50		10/23/20	USD	230.00	USD	1,096		(42,250	)
Tesla, Inc.		26		10/23/20	USD	425.00	USD	1,115		(102,050	)
Twilio, Inc., Class A		58		10/23/20	USD	255.00	USD	1,433		(61,480	)
Yandex NV, Class A		245		10/23/20	USD	64.50	USD	1,599		(86,975	)
Zoom Video Communications, Inc., Class A		50		10/23/20	USD	440.00	USD	2,351		(253,250	)
Zscaler, Inc.		164		10/23/20	USD	134.00	USD	2,307		(168,920	)
Activision Blizzard, Inc.		95		10/30/20	USD	85.00	USD	769		(15,580	)
Adobe, Inc.		31		10/30/20	USD	500.00	USD	1,520		(51,925	)
Advanced Micro Devices, Inc.		126		10/30/20	USD	85.50	USD	1,033		(59,535	)
Alibaba Group Holding Ltd., ADR		62		10/30/20	USD	272.50	USD	1,823		(163,370	)
Apple, Inc.		186		10/30/20	USD	120.00	USD	2,154		(74,400	)
Autodesk, Inc.		41		10/30/20	USD	250.00	USD	947		(13,018	)
Crowdstrike Holdings, Inc., Class A		79		10/30/20	USD	155.00	USD	1,085		(23,937	)
Facebook, Inc., Class A		17		10/30/20	USD	267.50	USD	445		(17,977	)
Lam Research Corp.		69		10/30/20	USD	345.00	USD	2,289		(92,287	)
Marvell Technology Group Ltd.		386		10/30/20	USD	41.00	USD	1,532		(45,162	)
MercadoLibre, Inc.		25		10/30/20	USD	1,040.00	USD	2,706		(209,125	)
Microsoft Corp.		8		10/30/20	USD	207.50	USD	168		(7,380	)
MongoDB, Inc.		49		10/30/20	USD	217.50	USD	1,134		(110,005	)
NetEase, Inc., ADR		25		10/30/20	USD	480.00	USD	1,137		(24,750	)
Netflix, Inc.		15		10/30/20	USD	510.00	USD	750		(40,162	)
PayPal Holdings, Inc.		146		10/30/20	USD	192.50	USD	2,877		(186,880	)
RingCentral, Inc., Class A		38		10/30/20	USD	300.00	USD	1,044		(28,310	)
Roku, Inc.		110		10/30/20	USD	220.00	USD	2,077		(42,075	)
Skyworks Solutions, Inc.		96		10/30/20	USD	145.00	USD	1,397		(67,200	)
Snap, Inc., Class A		63		10/30/20	USD	26.00	USD	164		(13,608	)
Square, Inc., Class A		215		10/30/20	USD	155.00	USD	3,495		(318,200	)
StoneCo Ltd., Class A		166		10/30/20	USD	55.00	USD	878		(34,860	)
Taiwan Semiconductor Manufacturing Co. Ltd., ADR		277		10/30/20	USD	80.50	USD	2,246		(121,187	)
Visa, Inc., Class A		37		10/30/20	USD	207.50	USD	740		(12,710	)
Yandex NV, Class A		245		10/30/20	USD	64.50	USD	1,599		(105,350	)
Zoom Video Communications, Inc., Class A		30		10/30/20	USD	530.00	USD	1,410		(50,550	)
Zscaler, Inc.		81		10/30/20	USD	145.00	USD	1,140		(58,522	)
Activision Blizzard, Inc.		130		11/06/20	USD	85.50	USD	1,052		(40,365	)
Adobe, Inc.		18		11/06/20	USD	515.00	USD	883		(26,640	)
Facebook, Inc., Class A		37		11/06/20	USD	270.00	USD	969		(45,140	)
Marvell Technology Group Ltd.		104		11/06/20	USD	40.50	USD	413		(14,508	)
MercadoLibre, Inc.		21		11/06/20	USD	1,150.00	USD	2,273		(106,050	)
Microsoft Corp.		92		11/06/20	USD	217.50	USD	1,935		(64,630	)
NetEase, Inc., ADR		27		11/06/20	USD	475.00	USD	1,228		(40,095	)
Okta, Inc.		105		11/06/20	USD	230.00	USD	2,245		(77,437	)
RingCentral, Inc., Class A		16		11/06/20	USD	300.00	USD	439		(17,200	)
salesforce.com, Inc.		65		11/06/20	USD	270.00	USD	1,634		(45,175	)
Visa, Inc., Class A		37		11/06/20	USD	210.00	USD	740		(14,708	)
Zoom Video Communications, Inc., Class A		47		11/06/20	USD	490.00	USD	2,210		(166,145	)
Advanced Micro Devices, Inc.		160		11/20/20	USD	87.50	USD	1,312		(86,800	)
Alibaba Group Holding Ltd., ADR		126		11/20/20	USD	280.00	USD	3,704		(329,490	)
Alphabet, Inc., Class A		10		11/20/20	USD	1,525.00	USD	1,466		(59,550	)
Avalara, Inc.		154		11/20/20	USD	130.00	USD	1,961		(160,160	)

CONSOLIDATED SCHEDULE OF INVESTMENTS 5

Consolidated Schedule of Investments  (unaudited) (continued) September 30, 2020 BlackRock Science and Technology Trust (BST)

Exchange-Traded Options Written (continued)

Description	Number of Contracts		Expiration Date		Exercise Price		Notional Amount (000)		Value
Call (continued)
Bandwidth, Inc., Class A		90		11/20/20	USD	150.00	USD	1,571	$	(284,850	)
Cadence Design Systems, Inc.		141		11/20/20	USD	110.00	USD	1,503		(71,205	)
Coupa Software, Inc.		74		11/20/20	USD	280.00	USD	2,029		(151,700	)
Elastic NV		98		11/20/20	USD	110.00	USD	1,057		(77,910	)
Facebook, Inc., Class A		9		11/20/20	USD	290.00	USD	236		(6,840	)
Fair Isaac Corp.		23		11/20/20	USD	450.00	USD	978		(38,755	)
Marvell Technology Group Ltd.		103		11/20/20	USD	41.00	USD	409		(21,424	)
Mastercard, Inc., Class A		31		11/20/20	USD	345.00	USD	1,048		(42,315	)
Microsoft Corp.		73		11/20/20	USD	220.00	USD	1,535		(52,012	)
Monolithic Power Systems, Inc.		55		11/20/20	USD	260.00	USD	1,538		(169,125	)
Okta, Inc.		91		11/20/20	USD	220.00	USD	1,946		(121,940	)
Paycom Software Inc.		70		11/20/20	USD	310.00	USD	2,179		(183,050	)
PayPal Holdings, Inc.		77		11/20/20	USD	195.00	USD	1,517		(110,880	)
Roku, Inc.		21		11/20/20	USD	195.00	USD	396		(37,485	)
ServiceNow, Inc.		42		11/20/20	USD	480.00	USD	2,037		(158,130	)
Shopify, Inc., Class A		13		11/20/20	USD	1,010.00	USD	1,330		(132,145	)
Snap, Inc., Class A		137		11/20/20	USD	27.00	USD	358		(29,866	)
Snowflake, Inc., Class A		30		11/20/20	USD	300.00	USD	753		(50,550	)
TAL Education Group, ADR		187		11/20/20	USD	82.50	USD	1,422		(52,827	)
Twilio, Inc., Class A		56		11/20/20	USD	260.00	USD	1,384		(106,120	)
Visa, Inc., Class A		27		11/20/20	USD	215.00	USD	540		(9,113	)
Yandex NV, Class A		41		11/20/20	USD	70.00	USD	268		(11,173	)
									$	(11,089,237	)

OTC Options Written

Description	Counterparty	Number of Contracts		Expiration Date		Exercise Price		Notional Amount (000)		Value
Call
Ping An Healthcare and Technology Co. Ltd.	JPMorgan Chase Bank N.A.		92,400		10/07/20	HKD	120.65	HKD	9,240	$	(36	)
Altium Ltd.	Morgan Stanley & Co. International PLC		37,400		10/14/20	AUD	37.26	AUD	1,358		(12,565	)
Meituan Dianping, Class B	Morgan Stanley & Co. International PLC		105,300		10/15/20	HKD	269.15	HKD	25,708		(47,110	)
SOITEC	Morgan Stanley & Co. International PLC		8,000		10/21/20	EUR	108.96	EUR	982		(136,573	)
GMO Payment Gateway, Inc.	JPMorgan Chase Bank N.A.		11,700		10/22/20	JPY	10,969.02	JPY	132,183		(71,539	)
STMicroelectronics NV	Credit Suisse International		31,300		10/22/20	EUR	26.02	EUR	819		(45,748	)
TeamViewer AG	Barclays Bank PLC		26,500		10/22/20	EUR	42.43	EUR	1,115		(46,391	)
Tencent Holdings Ltd.	Morgan Stanley & Co. International PLC		66,900		10/22/20	HKD	538.58	HKD	35,020		(93,702	)
Meituan Dianping, Class B	Citibank N.A.		96,400		10/27/20	HKD	243.60	HKD	23,535		(170,325	)
Renesas Electronics Corp.	JPMorgan Chase Bank N.A.		206,200		10/27/20	JPY	839.95	JPY	159,614		(22,575	)
Tencent Holdings Ltd.	UBS AG		68,000		10/27/20	HKD	534.97	HKD	35,596		(119,339	)
Altium Ltd.	Morgan Stanley & Co. International PLC		7,800		11/04/20	AUD	36.20	AUD	283		(8,282	)
Kakao Corp.	JPMorgan Chase Bank N.A.		7,400		11/04/20	USD	370,230.87	USD	2,691,085		(102,066	)
Kingdee International Software Group Co. Ltd.	JPMorgan Chase Bank N.A.		577,000		11/04/20	HKD	20.51	HKD	11,664		(109,077	)
Ping An Healthcare and Technology Co. Ltd.	JPMorgan Chase Bank N.A.		82,700		11/04/20	HKD	115.36	HKD	8,270		(12,038	)
SOITEC	Citibank N.A.		6,000		11/04/20	EUR	127.10	EUR	737		(23,704	)
STMicroelectronics NV	Credit Suisse International		27,400		11/04/20	EUR	26.71	EUR	717		(32,134	)
TeamViewer AG	Credit Suisse International		11,300		11/04/20	EUR	44.22	EUR	475		(14,602	)
ZoomInfo Technologies, Inc., Class A	UBS AG		42,300		11/05/20	USD	35.25	USD	1,818		(344,531	)
ASML Holding NV	UBS AG		7,000		11/06/20	EUR	324.30	EUR	2,203		(72,840	)
Kakao Corp.	JPMorgan Chase Bank N.A.		2,000		11/06/20	USD	382,130.00	USD	727,320		(20,699	)
Kingdee International Software Group Co. Ltd.	JPMorgan Chase Bank N.A.		297,000		11/06/20	HKD	20.03	HKD	6,004		(65,452	)
Samsung CDI Co. Ltd.	JPMorgan Chase Bank N.A.		6,400		11/06/20	USD	458,865.00	USD	2,765,022		(69,494	)
SOITEC	UBS AG		1,600		11/06/20	EUR	129.37	EUR	196		(5,204	)
Xero Ltd.	JPMorgan Chase Bank N.A.		21,000		11/06/20	AUD	95.32	AUD	2,139		(125,120	)
Tencent Music Entertainment Group, ADR	Credit Suisse International		69,800		11/09/20	USD	15.94	USD	1,031		(24,775	)
Adyen NV	Barclays Bank PLC		1,900		11/10/20	EUR	1,658.59	EUR	2,989		(88,389	)
Delivery Hero SE	Goldman Sachs International		9,200		11/10/20	EUR	102.74	EUR	900		(41,642	)
Inphi Corp.	JPMorgan Chase Bank N.A.		16,100		11/10/20	USD	111.00	USD	1,807		(119,302	)

6

Consolidated Schedule of Investments  (unaudited) (continued) September 30, 2020 BlackRock Science and Technology Trust (BST)

OTC Options Written (continued)

Description	Counterparty	Number of Contracts		Expiration Date		Exercise Price			Notional Amount (000)			Value
Call (continued)
SOITEC	Goldman Sachs International		8,000		11/10/20		EUR	127.82		EUR	982	$	(33,403	)
GMO Payment Gateway, Inc.	UBS AG		14,400		11/12/20		JPY	11,631.82		JPY	162,687		(58,014	)
TeamViewer AG	Credit Suisse International		21,700		11/12/20		EUR	43.49		EUR	913		(39,852	)
Xero Ltd.	Morgan Stanley & Co. International PLC		18,300		11/12/20		AUD	104.78		AUD	1,864		(33,015	)
Charles Schwab Corp.	JPMorgan Chase Bank N.A.		21,200		11/16/20		USD	70.96		USD	1,514		(111,014	)
Altium Ltd.	Morgan Stanley & Co. International PLC		45,500		11/18/20		AUD	37.00		AUD	1,652		(37,458	)
Kingdee International Software Group Co. Ltd.	JPMorgan Chase Bank N.A.		569,000		11/18/20		HKD	21.13		HKD	11,502		(78,008	)
ASML Holding NV	Morgan Stanley & Co. International PLC		12,800		11/19/20		EUR	323.23		EUR	4,028		(162,375	)
Delivery Hero SE	Goldman Sachs International		25,400		11/19/20		EUR	103.30		EUR	2,486		(150,006	)
SOITEC	UBS AG		2,400		11/19/20		EUR	126.79		EUR	295		(12,851	)
												$	(2,761,250	)

Fair Value Hierarchy as of Period End

Various inputs are used in determining the fair value of financial instruments. These inputs to valuation techniques are categorized into a fair value hierarchy consisting of three broad levels for financial reporting purposes as follows:

• Level 1 – Unadjusted price quotations in active markets/exchanges for identical assets or liabilities that the Trust has the ability to access

• Level 2 – Other observable inputs (including, but not limited to, quoted prices for similar assets or liabilities in markets that are active, quoted prices for identical or similar assets or liabilities in markets that are not active, inputs other than quoted prices that are observable for the assets or liabilities (such as interest rates, yield curves, volatilities, prepayment speeds, loss severities, credit risks and default rates) or other market–corroborated inputs)

• Level 3 – Unobservable inputs based on the best information available in the circumstances, to the extent observable inputs are not available (including the BlackRock Global Valuation Methodologies Committee’s (the “Global Valuation Committee’s”) assumptions used in determining the fair value of financial instruments)

The hierarchy gives the highest priority to unadjusted quoted prices in active markets for identical assets or liabilities (Level 1 measurements) and the lowest priority to unobservable inputs (Level 3 measurements). Accordingly, the degree of judgment exercised in determining fair value is greatest for instruments categorized in Level 3. The inputs used to measure fair value may fall into different levels of the fair value hierarchy. In such cases, for disclosure purposes, the fair value hierarchy classification is determined based on the lowest level input that is significant to the fair value measurement in its entirety. Investments classified within Level 3 have significant unobservable inputs used by the Global Valuation Committee in determining the price for Fair Valued Investments. Level 3 investments include equity or debt issued by privately held companies or funds. There may not be a secondary market, and/or there are a limited number of investors. The categorization of a value determined for financial instruments is based on the pricing transparency of the financial instruments and is not necessarily an indication of the risks associated with investing in those securities. For information about the Trust’s policy regarding valuation of financial instruments, refer to its most recent financial statements.

The following tables summarize the Trust’s investments and derivative financial instruments categorized in the disclosure hierarchy. The breakdown of the Trust’s investments into major categories is disclosed in the Consolidated Schedule of Investments above.

	Level 1		Level 2		Level 3		Total
Assets
Investments
Long-Term Investments
Common Stocks
Automobiles	$	12,497,061	$	—	$	—	$	12,497,061
Banks		—		—		11,167,128		11,167,128
Diversified Consumer Services		16,889,554		—		—		16,889,554
Diversified Financial Services		—		—		3,499,552		3,499,552
Diversified Telecommunication Services		8,774,063		—		—		8,774,063
Electronic Equipment, Instruments & Components		—		6,824,265		—		6,824,265
Entertainment		37,362,304		—		—		37,362,304
Health Care Technology		10,611,655		6,297,598		—		16,909,253
Interactive Media & Services		63,931,373		40,713,509		—		104,644,882
Internet & Direct Marketing Retail		83,129,186		29,477,920		253,889		112,860,995
IT Services		168,797,616		17,731,279		9,989,987		196,518,882
Semiconductors & Semiconductor Equipment		89,936,986		40,911,518		—		130,848,504
Software		210,298,771		34,071,427		8,352,801		252,722,999
Technology Hardware, Storage & Peripherals		44,870,469		—		—		44,870,469

CONSOLIDATED SCHEDULE OF INVESTMENTS 7

Consolidated Schedule of Investments  (unaudited) (continued) September 30, 2020 BlackRock Science and Technology Trust (BST)

Fair Value Hierarchy as of Period End (continued)

	Level 1			Level 2			Level 3		Total
Preferred Securities
Preferred Stocks	$	—		$	—		$	85,972,604	$	85,972,604
Warrants		—			—			180,718		180,718
Short-Term Securities
Money Market Funds		2,316,076			—			—		2,316,076
	$	749,415,114		$	176,027,516		$	119,416,679		1,044,859,309
Derivative Financial Instruments(a)
Liabilities
Equity Contracts	$	(11,005,081	)	$	(2,845,406	)	$	—	$	(13,850,487	)

^(a) Derivative financial instruments are options written. Options written are shown at value.

A reconciliation of Level 3 financial instruments is presented when the Trust had a significant amount of Level 3 investments at the beginning and/or end of the period in relation to net assets. The following table is a reconciliation of Level 3 investments for which significant unobservable inputs were used in determining fair value:

	Common Stocks		Preferred Stocks		Warrants		Total
Assets
Opening balance, as of December 31, 2019	$	11,498,561	$	47,488,016	$	19,454	$	59,006,031
Transfers into Level 3		—		—		—		—
Transfers out of Level 3		—		—		—		—
Accrued discounts/premiums		—		—		—		—
Net realized gain (loss)		—		—		—		—
Net change in unrealized appreciation (depreciation)(a)		5,114,693		8,130,677		161,264		13,406,634
Purchases		16,650,103		30,353,911		—		47,004,014
Sales		—		—		—		—
Closing balance, as of September 30, 2020	$	33,263,357	$	85,972,604	$	180,718	$	119,416,679
Net change in unrealized appreciation (depreciation) on investments still held at September 30, 2020(a)	$	5,114,693	$	8,130,677	$	161,264	$	13,406,634

^(a) Any difference between net change in unrealized appreciation (depreciation) and net change in unrealized appreciation (depreciation) on investments still held at September 30, 2020 is generally due to investments no longer held or categorized as Level 3 at period end.

The following table summarizes the valuation approaches used and unobservable inputs utilized by the BlackRock Global Valuation Methodologies Committee (the “Global Valuation Committee”) to determine the value of certain of the Trust’s Level 3 investments as of period end. The table does not include Level 3 investments with values based upon unadjusted third party pricing information in the amount of $3,999,569. A significant change in the third party information could result in a significantly lower or higher value of such Level 3 investments.

	Value		Valuation Approach	Unobservable Inputs	Range of Unobservable Inputs Utilized(a)		Weighted Average of Unobservable Inputs
Assets
Common Stocks(b)(c)	$	29,263,788	Market	Revenue Multiple		5.75x - 10.64x		7.59x
				Recent Transactions		-		-
Preferred Stocks(d)(e)(f)		85,972,604	Market	Revenue Multiple		2.50x - 21.50x		7.74x
				EBITDA Multiple		19.50x		-
				Volatility		39% - 61%		53%
				Time to Exit		3.0 - 5.0		3.3
				Recent Transactions		-		-
			Income	Discount Rate		14%		-
Warrants		180,718	Market	Revenue Multiple		9.08x		-
				Volatility		44%		-
				Time to Exit		0.5		-

8

Consolidated Schedule of Investments  (unaudited) (continued) September 30, 2020 BlackRock Science and Technology Trust (BST)

Value		Valuation Approach	Unobservable Inputs	Range of Unobservable Inputs Utilized(a)	Weighted Average of Unobservable Inputs
$	115,417,110

(a) A significant change in unobservable input would have resulted in a correlated (inverse) significant change to value.

(b) For the period end September 30, 2020, the valuation technique for investments classified as Common Stocks amounting to $11,167,128 changed to Transaction Price approach. The investments were previously valued utilizing Current Value Method. The change was due to consideration of the information that was available at the time the investments were valued.

(c) For the period end September 30, 2020, the valuation technique for investments classified as Common Stocks amounting to $5,990,419 changed to Transaction Price approach. The investments were previously valued utilizing Option Pricing Model approach. The change was due to consideration of the information that was available at the time the investments were valued.

(d) For the period end September 30, 2020, the valuation technique for investments classified as Preferred Stocks amounting to $4,985,815 changed to Transaction Price Approach. The investments were previously valued utilizing Current Value Method. The change was due to consideration of the information that was available at the time the investments were valued.

(e) For the period end September 30, 2020, the valuation technique for investments classified as Preferred Stocks amounting to $7,695,830 changed to Transaction Price Approach. The investments were previously valued utilizing Option Pricing Model approach. The change was due to consideration of the information that was available at the time the investments were valued.

(f) For the period end September 30, 2020, the valuation technique for investments classified as Preferred Stocks amounting to $15,727,824 changed to Current Value Method. The investments were previously valued utilizing Transaction Price Approach. The change was due to consideration of the information that was available at the time the investments were valued.

Currency Abbreviation
AUD	Australian Dollar
EUR	Euro
HKD	Hong Kong Dollar
JPY	Japanese Yen
USD	United States Dollar
Portfolio Abbreviation
ADR	American Depositary Receipt
CDI	CREST Depository Interest
OTC	Over-the-Counter

CONSOLIDATED SCHEDULE OF INVESTMENTS 9