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Unaudited Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Cash flows from operating activities    
Net loss $ (13,073) $ (11,216)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation expense 43 29
Non-cash interest expense (debt discount and deferred costs) 116 23
Change in fair value of warrants 104  
Stock-based compensation expense 822 629
Changes in assets and liabilities:    
Accounts receivable (156)  
Prepaid expenses and other current assets (372) (165)
Inventory (30) (274)
Deposits and other assets   78
Accounts payable 91 2,071
Accrued expenses and other current liabilities 656 1,331
Accrued interest 177 67
Deferred rent 6 (3)
Net cash used in operating activities (11,616) (7,430)
Cash flows from investing activities    
Capital expenditures (28) (37)
Sale of marketable securities 5,291  
Net cash provided by (used in) investing activities 5,263 (37)
Cash flows from financing activities    
Proceeds from issuance of common stock, net of issuance costs   40,888
Proceeds from exercise of stock options 181 2
Proceeds from notes payable, net of costs 5,000 2,500
Repayments of notes payable   (2,500)
Financing costs and discount of notes payable (104)  
Net cash provided by financing activities 5,077 40,890
Net (decrease) increase in cash and cash equivalents (1,276) 33,423
Cash and cash equivalents, at beginning of period 13,047 3,939
Cash and cash equivalents, at end of period 11,771 37,362
Supplemental disclosure of cash flow information    
Cash paid during the period for interest $ 368 $ 174