X0407 4 2023-05-17 0 0001616543 Senseonics Holdings, Inc. SENS 0001666972 Fiorentino Edward 20451 SENECA MEADOWS PARKWAY GERMANTOWN MD 20876-7005 1 0 0 0 0 Common Stock 2023-05-17 4 A 0 147948 0.00 A 743037 D Represents a restricted stock unit ("RSU") grant pursuant to the Issuer's non-employee director compensation policy. The RSUs vest in full on the earlier of the one year anniversary of the date of grant or the next annual stockholders meeting, subject to the Reporting Person's continuous service through such vesting date. Each RSU represents a contingent right to receive one share of the Issuer's common stock. /s/ Darren K. DeStefano, Attorney-in-Fact 2023-05-19