X0306 4 2018-04-02 0 0001616543 Senseonics Holdings, Inc. SENS 0001608710 Klein Peter Justin 1954 GREENSPRING DRIVE SUITE 600 TIMONIUM MD 21093 1 0 0 0 Common Stock 2018-04-02 4 A 0 3911 3.10 A 12510 D This common stock was issued to the reporting person pursuant to the Issuer's non-employee director compensation policy in lieu of quarterly retainer fees. The number of shares of common stock is equal to $12,125 divided by $3.10, the closing price of issuer's common stock on the NYSE American on April 2, 2018, the last trading day of the prior quarter. /s/ Sasha Keough, attorney-in-fact 2018-04-09