X0206 3 2020-08-18 0 0001802665 Harmony Biosciences Holdings, Inc. HRMY 0001615993 Dayno Jeffrey M. 630 W. GERMANTOWN PIKE, SUITE 215 PLYMOUTH MEETING PA 19462 0 1 0 0 Chief Medical Officer Stock Option 8.22 2027-11-13 Common Stock 103469 D Stock Option 8.22 2029-01-07 Common Stock 6086 D Stock Option 8.22 2030-03-04 Common Stock 12172 D The stock option is currently vested with respect to 41,387 shares, and will vest with respect to the remainder of the shares in three equal annual installments beginning on October 13, 2020. The stock option is currently vested with respect to 1,217 shares, and will vest with respect to the remander of the shares in four equal annual installments beginning on January 7, 2020. The stock option will vest in five equal annual installments beginning on March 4, 2021. Exhibit 24 - Power of Attorney. /s/ Stephanie Wisdo, Attorney-in-fact for Jeffrey Dayno 2020-08-18