0001104659-23-060784.txt : 20230515 0001104659-23-060784.hdr.sgml : 20230515 20230515161542 ACCESSION NUMBER: 0001104659-23-060784 CONFORMED SUBMISSION TYPE: 13F-HR/A PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20220930 FILED AS OF DATE: 20230515 DATE AS OF CHANGE: 20230515 EFFECTIVENESS DATE: 20230515 FILER: COMPANY DATA: COMPANY CONFORMED NAME: VR Adviser, LLC CENTRAL INDEX KEY: 0001615982 IRS NUMBER: 464814731 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR/A SEC ACT: 1934 Act SEC FILE NUMBER: 028-20281 FILM NUMBER: 23922551 BUSINESS ADDRESS: STREET 1: 7 BRYANT PARK STREET 2: 23RD FLOOR CITY: NEW YORK STATE: NY ZIP: 10018 BUSINESS PHONE: 650-475-3734 MAIL ADDRESS: STREET 1: 7 BRYANT PARK STREET 2: 23RD FLOOR CITY: NEW YORK STATE: NY ZIP: 10018 13F-HR/A 1 primary_doc.xml X0202 13F-HR/A LIVE false false false 0001615982 XXXXXXXX 09-30-2022 09-30-2022 true 1 RESTATEMENT false VR Adviser, LLC

7 Bryant Park 23rd Floor New York NY 10018

13F HOLDINGS REPORT 028-20281 Y Note: VR Adviser, LLC is filing this Form 13F on behalf of itself and the general partner entities of the investment funds for which it serves as the investment adviser, VHCP Management II, LLC, VHCP Management III, LLC and VHCP Management EG, LLC. Note: This amendment is being filed solely to remove holdings of securities of DBV Technologies S A ("DBV") from the reporting manager's holdings of 13(f) securities as of September 30, 2022. The reporting manager's holdings of DBV equity securities as of September 30 2022 consisted of ordinary shares, which are not considered "Section 13(f) securities" and are, therefore, not reportable on Form 13F, in contrast to American depositary shares, which are reportable on Form 13F. This amendment does not reflect the disposition of any securities of DBV by the reporting manager, but merely reflects the fact that the holdings as of September 30, 2022 were in the form of ordinary shares. As of September 30, 2022, the reporting manager's holdings included 9,300,000 ordinary shares of DBV. Sherman G. Souther 650-561-9580 /s/ Sherman G. Souther Palo Alto CA 05-15-2023 0 31 648091000 INFORMATION TABLE 2 infotable.xml aTyr Pharma Inc COM 002120202 4197000 1398889 SH SOLE 1398889 0 0 Aclaris Therapeutics Inc COM 00461U105 71837000 4563962 SH SOLE 4563962 0 0 Aerovate Therapeutics Inc COM 008064107 13827000 833927 SH SOLE 833927 0 0 Affimed NV COM N01045108 2943000 1428571 SH SOLE 1428571 0 0 Akouos Inc COM 00973J101 18932000 2800566 SH SOLE 2800566 0 0 Altimmune Inc COM 02155H200 4716000 369306 SH SOLE 369306 0 0 Annexon Inc COM 03589W102 19900000 3220050 SH SOLE 3220050 0 0 Celldex Therapeutics Inc COM 15117B202 2108000 75000 SH SOLE 75000 0 0 Cogent Biosciences Inc COM 19240Q201 60249000 4038117 SH SOLE 4038117 0 0 Dice Therapeutics Inc COM 23345J104 15514000 764979 SH SOLE 764979 0 0 Fulcrum Therapeutics Inc COM 359616109 9708000 1200000 SH SOLE 1200000 0 0 GH Research PLC ORD SH G3855L106 38731000 3333154 SH SOLE 3333154 0 0 Gossamer Bio Inc COM 38341P102 20929000 1747000 SH SOLE 1747000 0 0 Immunocore Holdings PLC ADS 45258D105 4441000 94605 SH SOLE 94605 0 0 Inozyme Pharma Inc COM 45790W108 7263000 2709987 SH SOLE 2709987 0 0 Instil Bio Inc COM 45783C101 19872000 4105779 SH SOLE 4105779 0 0 LianBio SPONS ADR 53000N108 10757000 5378341 SH SOLE 5378341 0 0 Lyra Therapeutics Inc COM 55234L105 4630000 924170 SH SOLE 924170 0 0 Marinus Pharmaceuticals Inc COM 56854Q200 20993000 3156803 SH SOLE 3156803 0 0 Milestone Pharmaceuticals Inc COM 59935V107 22293000 2425737 SH SOLE 2425737 0 0 Pliant Therapeutics Inc COM 729139105 22561000 1080000 SH SOLE 1080000 0 0 Prometheus Biosciences Inc COM 74349U108 7179000 121663 SH SOLE 121663 0 0 Provention Bio Inc COM 74374N102 5034000 1118653 SH SOLE 1118653 0 0 Rallybio Corp COM 75120L100 3886000 268532 SH SOLE 268532 0 0 Relmada Therapeutics Inc COM 75955J402 56198000 1518056 SH SOLE 1518056 0 0 Savara Inc COM 805111101 7060000 4555038 SH SOLE 4555038 0 0 Terns Pharmaceuticals Inc COM 880881107 21839000 3707891 SH SOLE 3707891 0 0 Trevi Therapeutics Inc COM 89532M101 4697000 3050022 SH SOLE 3050022 0 0 Tricida Inc COM 89610F101 94845000 9050064 SH SOLE 9050064 0 0 Ventyx Biosciences Inc COM 92332V107 7259000 207925 SH SOLE 207925 0 0 Viridian Therapeutics Inc COM 92790C104 43693000 2130308 SH SOLE 2130308 0 0