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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (Unaudited) - USD ($)
Total
Preferred Stock
Common Stock
Additional Paid-In Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Preferred stock, beginning balance (shares) at Dec. 31, 2017   0        
Equity, beginning balance at Dec. 31, 2017 $ 29,105,888 $ 0 $ 1,780 $ 140,184,630 $ (1,247) $ (111,079,275)
Common stock, beginning balance (shares) at Dec. 31, 2017     17,797,178      
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Vesting of restricted common stock (shares)     171,029      
Vesting of restricted common stock 0   $ 17 (17)    
Issuance of common stock from option exercises (shares)     12,645      
Issuance of common stock from option exercises 54,913   $ 1 54,912    
Stock-based compensation expense 908,940     908,940    
Unrealized gain (loss) on available-for-sale securities 1,340       1,340  
Net loss (8,223,227)         (8,223,227)
Preferred stock, ending balance (shares) at Mar. 31, 2018   0        
Equity, ending balance at Mar. 31, 2018 21,888,071 $ 0 $ 1,798 141,148,465 93 (119,262,285)
Common stock, ending balance (shares) at Mar. 31, 2018     17,980,852      
Preferred stock, beginning balance (shares) at Dec. 31, 2017   0        
Equity, beginning balance at Dec. 31, 2017 29,105,888 $ 0 $ 1,780 140,184,630 (1,247) (111,079,275)
Common stock, beginning balance (shares) at Dec. 31, 2017     17,797,178      
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Unrealized gain (loss) on available-for-sale securities 1,247          
Net loss (17,275,099)          
Preferred stock, ending balance (shares) at Jun. 30, 2018   0        
Equity, ending balance at Jun. 30, 2018 13,410,196 $ 0 $ 1,807 141,722,546 0 (128,314,157)
Common stock, ending balance (shares) at Jun. 30, 2018     18,066,142      
Preferred stock, beginning balance (shares) at Mar. 31, 2018   0        
Equity, beginning balance at Mar. 31, 2018 21,888,071 $ 0 $ 1,798 141,148,465 93 (119,262,285)
Common stock, beginning balance (shares) at Mar. 31, 2018     17,980,852      
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Vesting of restricted common stock (shares)     625      
Vesting of restricted common stock 0          
Issuance of common stock from option exercises (shares)     84,665      
Issuance of common stock from option exercises 63,097   $ 9 63,088    
Stock-based compensation expense 510,993     510,993    
Unrealized gain (loss) on available-for-sale securities (93)       (93)  
Net loss (9,051,872)         (9,051,872)
Preferred stock, ending balance (shares) at Jun. 30, 2018   0        
Equity, ending balance at Jun. 30, 2018 $ 13,410,196 $ 0 $ 1,807 141,722,546 0 (128,314,157)
Common stock, ending balance (shares) at Jun. 30, 2018     18,066,142      
Preferred stock, beginning balance (shares) at Dec. 31, 2018 0 0        
Equity, beginning balance at Dec. 31, 2018 $ 9,282,756 $ 0 $ 1,807 142,242,224 0 (132,961,275)
Common stock, beginning balance (shares) at Dec. 31, 2018 18,067,392   18,067,392      
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Vesting of restricted common stock (shares)     625      
Vesting of restricted common stock $ 0          
Stock-based compensation expense 220,975     220,975    
Net loss (2,230,430)         (2,230,430)
Preferred stock, ending balance (shares) at Mar. 31, 2019   0        
Equity, ending balance at Mar. 31, 2019 $ 7,273,301 $ 0 $ 1,807 142,463,199 0 (135,191,705)
Common stock, ending balance (shares) at Mar. 31, 2019     18,068,017      
Preferred stock, beginning balance (shares) at Dec. 31, 2018 0 0        
Equity, beginning balance at Dec. 31, 2018 $ 9,282,756 $ 0 $ 1,807 142,242,224 0 (132,961,275)
Common stock, beginning balance (shares) at Dec. 31, 2018 18,067,392   18,067,392      
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Issuance of common stock from option exercises (shares) 0          
Unrealized gain (loss) on available-for-sale securities $ 0          
Net loss $ (3,615,207)          
Preferred stock, ending balance (shares) at Jun. 30, 2019 0 0        
Equity, ending balance at Jun. 30, 2019 $ 6,101,071 $ 0 $ 1,807 142,675,746 0 (136,576,482)
Common stock, ending balance (shares) at Jun. 30, 2019 18,068,642   18,068,642      
Preferred stock, beginning balance (shares) at Mar. 31, 2019   0        
Equity, beginning balance at Mar. 31, 2019 $ 7,273,301 $ 0 $ 1,807 142,463,199 0 (135,191,705)
Common stock, beginning balance (shares) at Mar. 31, 2019     18,068,017      
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Vesting of restricted common stock (shares)     625      
Vesting of restricted common stock 0          
Stock-based compensation expense 212,547     212,547    
Unrealized gain (loss) on available-for-sale securities 0          
Net loss $ (1,384,777)         (1,384,777)
Preferred stock, ending balance (shares) at Jun. 30, 2019 0 0        
Equity, ending balance at Jun. 30, 2019 $ 6,101,071 $ 0 $ 1,807 $ 142,675,746 $ 0 $ (136,576,482)
Common stock, ending balance (shares) at Jun. 30, 2019 18,068,642   18,068,642