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Quarterly financial information (unaudited) (Tables)
 12 Months Ended
Dec. 31, 2015
Quarterly Financial Information Disclosure [Abstract]  
Schedule of quarterly financial information
 
First Quarter Ended
March 31, 2015
 
Second Quarter
Ended
 June 30, 2015
 
Third Quarter Ended
September 30, 2015
 
Fourth Quarter Ended
December 31, 2015
Operating expenses:
 

 
 
 
 
 
 
Research and development
$
2,804,946

 
$
3,190,178

 
$
3,445,200

 
$
3,309,055

Selling, general and administrative
3,216,212

 
3,904,403

 
4,722,281

 
4,621,383

Total operating expenses
6,021,158

 
7,094,581

 
8,167,481

 
7,930,438

Loss from operations
(6,021,158
)
 
(7,094,581
)
 
(8,167,481
)
 
(7,930,438
)
Interest income, net
3,577

 
16,183

 
14,637

 
37,631

Net loss
$
(6,017,581
)
 
$
(7,078,398
)
 
$
(8,152,844
)
 
$
(7,892,807
)
Net loss per share attributable to common stockholders — basic and diluted
$
(0.59
)
 
$
(0.47
)
 
$
(0.53
)
 
$
(0.51
)
Weighted-average number of common shares outstanding — basic and diluted
10,179,955

 
15,034,764

 
15,290,435

 
15,551,800




 
Period from
February 26, 2014
(Inception) to
March 31, 2014
 
Second Quarter
Ended
 June 30, 2014
 
Third Quarter Ended
September 30, 2014
 
Fourth Quarter Ended
December 31, 2014
Operating expenses:
 

 
 
 
 
 
 
Research and development
$
30,023

 
$
1,099,644

 
$
909,123

 
$
1,965,121

Selling, general and administrative
62,700

 
1,092,665

 
1,084,240

 
1,786,290

Total operating expenses
92,723

 
2,192,309

 
1,993,363

 
3,751,411

Loss from operations
(92,723
)
 
(2,192,309
)
 
(1,993,363
)
 
(3,751,411
)
Interest income, net
—

 
2,658

 
6,926

 
9,362

Net loss
$
(92,723
)
 
$
(2,189,651
)
 
$
(1,986,437
)
 
$
(3,742,049
)
Net loss per share attributable to common stockholders — basic and diluted
$
(0.07
)
 
$
(1.42
)
 
$
(1.11
)
 
$
(1.82
)
Weighted-average number of common shares outstanding — basic and diluted
1,370,125

 
1,539,463

 
1,797,664

 
2,061,132