X0407 4 2023-03-21 1 0001615055 IsoPlexis Corp ISO 0001876594 Conley John G. C/O ISOPLEXIS CORPORATION 35 NE INDUSTRIAL ROAD BRANFORD CT 06405 1 0 0 0 0 Common Stock 2023-03-21 4 D 0 100752 D 0 D Stock Option 1.83 2023-03-21 4 D 0 8000 D 2030-12-14 Common Stock 8000 0 D Stock Option 10.7163 2023-03-21 4 D 0 40000 D 2031-07-21 Common Stock 40000 0 D Stock Option 2.10 2023-03-21 4 D 0 89047 D 2032-06-16 Common Stock 89047 0 D On March 21, 2023, pursuant to the Agreement and Plan of Merger, dated as of December 21, 2022 (the Merger Agreement), by and among IsoPlexis Corporation, a Delaware corporation (IsoPlexis), Berkeley Lights, Inc., a Delaware corporation (Berkeley Lights), and Iceland Merger Sub Inc., a Delaware corporation and a wholly owned subsidiary of Berkeley Lights, each share of common stock, par value $0.001, of IsoPlexis (IsoPlexis Common Stock) reported in this Form 4 was converted into the right to receive 0.6120 fully paid and nonassessable shares of common stock, par value $0.00005, of Berkeley Lights (Berkeley Lights Common Stock), together with cash in lieu of fractional shares of Berkeley Lights Common Stock, if any, and any unpaid dividends or other distributions. On March 21, 2023, pursuant to the Merger Agreement, each IsoPlexis stock option reported in this Form 4 that was (a) vested and unexercised or (b) vested solely as a result of the consummation of the merger pursuant to the Merger Agreement was, in each case, exercisable prior to the effective time of such merger and, to the extent unexercised at such effective time, canceled for no consideration. Vested 25% on December 15, 2021 and thereafter in 36 equal monthly installments. Vested 25% on July 19, 2022 and thereafter in 36 equal monthly installments. Vests in full on the earlier of June 16, 2023 or the day prior to the next annual stockholders meeting. /s/ John G. Conley 2023-03-21