X0306 4 2015-04-21 0 0001501756 Avalanche Biotechnologies, Inc. AAVL 0001614869 Blumenkranz Mark S. C/O AVALANCHE BIOTECHNOLOGIES, INC. 1035 O'BRIEN DRIVE, SUITE A MENLO PARK CA 94025 1 0 0 0 Common Stock 2015-04-21 4 A 0 2000 0.00 A 597989 D Common Stock 11531 I See Footnote Common Stock 11531 I See Footnote Common Stock 11531 I See Footnote Stock Option (Right to Buy) 39.35 2015-04-21 4 A 0 7000 0.00 A 2016-06-26 2025-04-20 Common Stock 7000 7000 D Restricted Stock Units ("RSUs"). The Reporting Person is entitled to receive one (1) share of Common Stock of the Issuer for each one (1) RSU upon the vesting thereof. Such RSUs vest with respect to 100% of the shares subject thereto on June 26, 2016. The shares are held directly by the Carla Helene Blumenkranz Irrevocable Trust. The shares are held directly by the Erik Davis Blumenkranz Irrevocable Trust. The shares are held directly by the Scott Aubrey Blumenkranz Irrevocable Trust. /s/ Michael Swartzburg, Attorney-in-Fact for Mark Blumenkranz 2015-04-23