X0306 4 2018-02-07 0 0001484565 SOLENO THERAPEUTICS INC SLNO 0001614821 Anish Bhatnagar 1235 RADIO ROAD, SUITE 110 REDWOOD CITY CA 94065 1 1 0 0 President and CEO Employee stock option (right to buy) 1.60 2018-02-07 4 A 0 400000 0.00 A 2028-02-07 Common Stock 400000 400000 D Restricted Stock Units 2018-02-07 4 A 0 100625 0.00 A Common Stock 100625 100625 D One forty-eighth (1/48) of the shares subject to the Option shall vest on the first month anniversary of February 7, 2018 (the "Vesting Commencement Date"), and one forty-eighth (1/48) of the total number of shares subject to the Option shall vest each month thereafter on the same day of the month as the Vesting Commencement Date (which is February 7, 2018), such that all of the shares subject to the Option will have vested as of the fourth anniversary of the Vesting Commencement Date, subject to Participant continuing to be a Service Provider through each such date. One hundred percent (100%) of the restricted stock units shall be deemed vested as of the transaction date (which is February 7, 2018). Each Restricted Stock Unit represents a right to receive one share of Soleno Therapeutics, Inc. Common Stock. /s/ Anish Bhatnagar 2018-02-08