SCHEDULE 13G 0001446580 XXXXXXXX LIVE Ordinary Shares, no par value per share 12/31/2025 0001614744 Purple Biotech Ltd. 74638P208 4 Oppenheimer Street Science Park Rehovot L3 7670104 Rule 13d-1(b) Susquehanna Securities, LLC DE 93953400 93953400 93953400 93953400 93953400 5.2 BD OO Purple Biotech Ltd. 4 Oppenheimer Street, Science Park, Rehovot 7670104, Israel This statement is filed by Susquehanna Securities, LLC, who is referred to herein as the "Reporting Person" with respect to the shares of Ordinary Shares, no par value per share (the "Shares"), of Purple Biotech Ltd. (the "Company"). The address of the principal business office of the Reporting Person is: 401 E. City Avenue Suite 220 Bala Cynwyd, PA 19004 Citizenship is set forth in Row 4 of the cover page for the Reporting Person and is incorporated herein by reference. N BD The information required by this Item 4(a) is set forth in Row 9 of the cover page for the Reporting Person and is incorporated herein by reference. The number of Shares reported as beneficially owned by Susquehanna Securities, LLC consists of 469,767 ADSs. Each ADS represents two hundred (200) Shares. The Company's Notice of Extraordinary General Meeting of Shareholders attached as Exhibit 99.1 to the Company's Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 of the Securities Exchange Act of 1934 on Form 6-K, filed October 28, 2025 indicates that there were 1,806,089,801 Shares outstanding as of October 20, 2025. 5.2 The information required by this Item 4(c)(i) is set forth in Row 5 of the cover page for the Reporting Person and is incorporated herein by reference. The information required by this Item 4(c)(ii) is set forth in Row 6 of the ccover page for the Reporting Person and is incorporated herein by reference. The information required by this Item 4(c)(iii) is set forth in Row 7 of the cover page for the Reporting Person and is incorporated herein by reference. The information required by this Item 4(c)(iv) is set forth in Row 8 of the cover page for the Reporting Person and is incorporated herein by reference. Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. Susquehanna Securities, LLC /s/ Brian Sopinsky 02/12/2026