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Development and License Agreements (Details Narrative) - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Mar. 31, 2022
Oct. 15, 2021
Dec. 31, 2022
Dec. 31, 2021
Mar. 31, 2021
Sep. 30, 2019
Jul. 31, 2019
Nov. 30, 2018
Dec. 31, 2016
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Dec. 31, 2022
Dec. 31, 2019
Jun. 30, 2020
Mar. 31, 2019
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
Development and license agreements description                       The academic COMBACTE-NET consortium partners initially pay for all costs incurred at EU clinical sites and subsequently bills the Company for 25% of such costs. Specifically, we are billed for 25% of eligible costs during the entire fiscal year six to seven months following the fiscal year. The work at these sites is performed entirely by third-party subcontractors. As such, we reimburse the 25% at the passed-through invoice amounts. There is no reimbursement for costs incurred at non-EU sites.          
Research and development expense                   $ 175,000 $ 6,118,000 $ 10,374,000 $ 18,916,000        
Liabilities     $ 38,927,000             18,336,000   18,336,000   $ 38,927,000      
Gain or loss on disposition                       0          
License revenue                   417,000 399,000 21,146,000 1,878,000        
License [Member]                                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
License revenue                   19,602,000        
Cystic Fibrosis Foundation Development Agreement [Member]                                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
Amount of award     7,600,000         $ 7,500,000 $ 2,900,000                
Award, upfront payment received                 $ 200,000                
Additional amount of award     150,000                            
License revenue                   400,000 100,000 1,300,000 700,000        
Grants Foundation Grant Agreement [Member]                                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
Revenue recognized                   0 400,000 200,000 600,000        
Grants Foundation Grant Agreement [Member] | Bill and Melinda Gates Foundation [Member]                                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
Amount of compensation   $ 1,930,000                              
Upfront payment received   $ 1,930,000                              
Serum License Agreement [Member]                                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
Upfront payment received           $ 15,000,000 $ 5,000,000                    
Liability revenue           $ 5,000,000                      
Fair value of net proceeds                             $ 5,000,000.0    
Fair value of gross proceeds                             5,400,000    
Issuance costs from equity allocation                             $ 441,000    
Deferred revenue from equity allocation                   4,600,000   4,600,000          
Contractual liability                       19,600,000          
Deferred revenue based on upfront payments                       15,000,000.0          
License fees                       19,600,000          
Deferred revenue based on upfront payments                   15,000,000.0   15,000,000.0          
Contractual liability                   19,600,000   19,600,000          
Serum License Agreement [Member] | License and Service [Member]                                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
Contractual liability                   14,500,000   14,500,000          
Serum License Agreement [Member] | Development Support Services [Member]                                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
Business development support services                       79,000          
Serum License Agreement [Member] | Research and Development Option [Member]                                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
Contractual liability                   892,000   892,000          
Serum License Agreement [Member] | Manufacturing Rights Option [Member]                                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
Manufacturing rights option                       4,100,000          
Serum License Agreement [Member] | License [Member]                                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
License revenue                   0   19,600,000          
Kermode Licensing and Product Discovery Agreement [Member]                                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
Revenue recognized                   0 $ 100,000 100,000 $ 500,000        
Maximum additional payments entitled       $ 250,000               250,000          
Gross transaction price $ 1,000,000                                
Kermode Licensing and Product Discovery Agreement [Member] | Research and Development Option [Member]                                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
Nonrefundable upfront payment 500,000                                
Nonrefundable milestone payments $ 500,000                                
Kermode Licensing and Product Discovery Agreement [Member] | License [Member]                                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
Upfront payment received         $ 500,000                        
Non-EUSites [Member]                                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
Research and development expense                   700,000   1,400,000   5,500,000      
EU Site [Member]                                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
Research and development expense                   $ 0   $ 2,300,000   3,800,000      
Cost incurred percent                   25.00%   25.00%          
Gross expenses contributed services amount                   $ 0   $ 1,700,000   2,900,000      
Liabilities     $ 1,000,000.0             $ 600,000   600,000   1,000,000.0      
Several Development Based Milestones [Member] | Cystic Fibrosis Foundation Development Agreement [Member]                                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
Probable transaction price performance obligations                                 $ 1,700,000
One Development Based Milestone in Progress [Member] | Cystic Fibrosis Foundation Development Agreement [Member]                                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
Amount of probable variable consideration                                 $ 1,000,000.0
Amount of probable variable consideration                               $ 1,000,000.0  
Four Develpoment Based Milestones [Member] | Cystic Fibrosis Foundation Development Agreement [Member]                                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
Amount of variable consideration                       3,800,000          
Amount of total variable consideration                           $ 3,900,000      
Three Develpoment Based Milestones [Member] | Cystic Fibrosis Foundation Development Agreement [Member]                                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
Amount of variable consideration                       $ 3,600,000          
Restricted Stock [Member] | Serum License Agreement [Member]                                  
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                  
Restricted common stock issuance             801,820                    
Private placement, value             $ 10,000,000